Evidence map›Paper›PMID 25173275›Full record

ArticleThe Review of scientific instruments2014

A new ion sensing deep atomic force microscope.

Barney Drake, Connor Randall, Daniel Bridges, Paul K Hansma

Open access · greenAbstract read
In one paragraph

Article in The Review of scientific instruments, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Barney DrakeDepartment of Physics, University of California, Santa Barbara, California 93106, USA.
Connor RandallDepartment of Physics, University of California, Santa Barbara, California 93106, USA.
Daniel BridgesDepartment of Physics, University of California, Santa Barbara, California 93106, USA.
Paul K HansmaDepartment of Physics, University of California, Santa Barbara, California 93106, USA.
University of California, Santa Barbara · US

Funding

Single-Molecule Pullers with Improved Force ResolutionR01GM065354 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI HANSMA, PAUL K · 2002 to 2014
$3.7M
NIGMS NIH HHS R01 GM065354
6 · The paper itself

Abstract

Here we describe a new deep atomic force microscope (AFM) capable of ion sensing. A novel probe assembly incorporates a micropipette that can be used both for sensing ion currents and as the tip for AFM imaging. The key advance of this instrument over previous ion sensing AFMs is that it uses conventional micropipettes in a novel suspension system. This paper focuses on sensing the ion current passively while using force feedback for the operation of the AFM in contact mode. Two images are obtained simultaneously: (1) an AFM topography image and (2) an ion current image. As an example, two images of a MEMS device with a microchannel show peaks in the ion current as the pipette tip goes over the edges of the channel. This ion sensing AFM can also be used in other modes including tapping mode with force feedback as well as in non-contact mode by utilizing the ion current for feedback, as in scanning ion conductance microscopy. The instrument is gentle enough to be used on some biological samples such as plant leaves.

Indexed as

IonsMicroscopy, Atomic ForceIons

Identifiers

PMID25173275
PMCPMC4149697
OpenAlexW2032259326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.