Evidence map›Paper›PMID 25173198›Full record

Observational studyIndian heart journal

Effect of PUFA on patients with hypertension: a hospital based study.

Nisha Shantakumari, Rasha Ali Eldeeb, Salwa Abdelzaher Mabrouk Ibrahim, Jayadevan Sreedharan, Sufian Otoum

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nisha ShantakumariAsst. Professor, Department of Physiology, Gulf Medical University, Ajman, P.O. Box: 4184, United Arab Emirates. Electronic address: nisha@gmu.ac.ae.
Rasha Ali EldeebAsst. Professor, Department of Physiology, Gulf Medical University, Ajman, P.O. Box: 4184, United Arab Emirates.
Salwa Abdelzaher Mabrouk IbrahimDepartment of Internal Medicine, Gulf Medical College Hospital, Ajman, United Arab Emirates.
Jayadevan SreedharanResearch Division, Gulf Medical University, Ajman, United Arab Emirates.
Sufian OtoumCollege of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates.
Gulf Medical University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension affects more than a quarter of the global adult population. Studies conducted worldwide suggest an overall small, yet useful, role of omega-3 PUFAs in reducing blood pressure in hypertensive patients. However there is no substantial data in this regard from population based in Middle East and Asia.

objectivesTo determine the effects of (omega-3) PUFA supplementation on the blood pressure of hypertensive patient. To identify if male and female hypertensive patients respond differently to PUFA. To identify if response of hypertensive patients to PUFA varies with the duration of hypertension and co-existence of diabetes/dyslipidemia. MATERIALS AND

methodsThis observational study was conducted among hypertensive patients visiting OPD of the Gulf Medical College Hospital, Ajman, UAE, during the period Jan-Dec 2012. A total of 100 hypertensive patients on treatment with their antihypertensive medications, 50 of whom were taking n-3 PUFA supplementation, were followed up for a period of 3 months. Comparisons were drawn between the BP recordings at the time of enrollment in the study and their follow up values 3 months after enrollment.

resultsThere was a statistically significant reduction in both the systolic and diastolic blood pressures after 3 months of PUFA therapy. The BP lowering effect of PUFA was more in males. A statistically significant reduction in BP was noted in non-diabetic patients and patients with long standing hypertension.

conclusionFindings of the study suggest that omega-3 PUFA dietary supplements augment the benefits of pharmacotherapy in hypertension.

Indexed as

Fatty Acids, Omega-3FemaleHumansHypertensionMaleMiddle AgedTreatment OutcomeUnited Arab EmiratesFatty Acids, Omega-3HypertensionPUFASupplements

Identifiers

PMID25173198
PMCPMC4150041
OpenAlexW1986330546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.