Evidence map›Paper›PMID 25173194›Full record

ArticleVirology2014

Nine additional complete genome sequences of HCV genotype 6 from Vietnam including new subtypes 6xb and 6xc.

Chunhua Li, Van H Pham, Kenji Abe, Ling Lu

Abstract read
In one paragraph

Article in Virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chunhua LiDepartment of Pathology and Laboratory Medicine, Center for Viral Oncology, University of Kansas Medical Center, MS 3046, 3901 Rainbow Boulevard, Kansas City, KS 66160, United States of America.
Van H PhamCenter for Molecular Biomedicine, School of Medicine, University of Medicine and Pharmacy in Ho Chi Minh City, Ho Chi Minh City, Vietnam; Molecular Diagnostics Section, The NK-BIOTEK Laboratory, Ho Chi Minh City, Vietnam.
Kenji AbeCenter for Molecular Biomedicine, School of Medicine, University of Medicine and Pharmacy in Ho Chi Minh City, Ho Chi Minh City, Vietnam; Molecular Diagnostics Section, The NK-BIOTEK Laboratory, Ho Chi Minh City, Vietnam; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Ling LuDepartment of Pathology and Laboratory Medicine, Center for Viral Oncology, University of Kansas Medical Center, MS 3046, 3901 Rainbow Boulevard, Kansas City, KS 66160, United States of America. Electronic address: llu@kumc.edu.

Funding

HCV Genotype 6: A Model for HCV Genetics and Molecular Epidemiology StudiesR01AI080734 · NIAID · UNIVERSITY OF UTAH · PI LU, LING · 2009 to 2011
$1.1M
NIAID NIH HHS 5R01AI080734-03ANIAID NIH HHS R01 AI080734
6 · The paper itself

Abstract

We completely sequenced nine HCV-6 variants from Vietnam. They are grouped into six lineages beyond the 24 assigned subtypes, 6a-6xa, and 14 unclassified lineages that have been recently described with full-length genomes. Co-analysis with reference sequences in the NS5B region identified additional 22 such lineages, which made the total taxonomic number of HCV-6 increased to 66 that might be recognized at the subtype level. Because two of these six lineages revealed in this study each had >3 epidemiologically unlinked isolates identified, we proposed to assign them new subtypes 6xb and 6xc in following the eXtended format recently recommended in the expanded HCV nomenclature.

Indexed as

Genome, ViralGenotypeHepacivirusHepatitis CHumansMolecular Sequence DataPhylogenyVietnamFull-length genomeGenotype 6HCVSequence

Identifiers

PMID25173194
PMCPMC4346185

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.