ArticleThe Journal of physiology2014
Rapid mapping of visual receptive fields by filtered back projection: application to multi-neuronal electrophysiology and imaging.
Article in The Journal of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina.PLoS computational biology · 2024Article
- Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine cells.eLife · 2023Article
- Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine cells.bioRxiv : the preprint server for biology · 2023Article
- Current Methods to Investigate Nociception and Pain in Zebrafish.Frontiers in neuroscience · 2021Review
- Article
- The dynamic receptive fields of retinal ganglion cells.Progress in retinal and eye research · 2018Review
- In vivo measurement of afferent activity with axon-specific calcium imaging.Nature neuroscience · 2018Article
- Functional Compartmentalization within Starburst Amacrine Cell Dendrites in the Retina.Cell reports · 2018Article
- Leveraging Zebrafish to Study Retinal Degenerations.Frontiers in cell and developmental biology · 2018Review
- Orientation-Selective Retinal Circuits in Vertebrates.Frontiers in neural circuits · 2018Review
- Time course of EPSCs in ON-type starburst amacrine cells is independent of dendritic location.The Journal of physiology · 2016Article
- In vivo physiological recording from the lateral line of juvenile zebrafish.The Journal of physiology · 2016Article
- Neural Mechanisms Generating Orientation Selectivity in the Retina.Current biology : CB · 2016Article
- General features of the retinal connectome determine the computation of motion anticipation.eLife · 2015Article
- Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Neurons in the visual system vary widely in the spatiotemporal properties of their receptive fields (RFs), and understanding these variations is key to elucidating how visual information is processed. We present a new approach for mapping RFs based on the filtered back projection (FBP), an algorithm used for tomographic reconstructions. To estimate RFs, a series of bars were flashed across the retina at pseudo-random positions and at a minimum of five orientations. We apply this method to retinal neurons and show that it can accurately recover the spatial RF and impulse response of ganglion cells recorded on a multi-electrode array. We also demonstrate its utility for in vivo imaging by mapping the RFs of an array of bipolar cell synapses expressing a genetically encoded Ca(2+) indicator. We find that FBP offers several advantages over the commonly used spike-triggered average (STA): (i) ON and OFF components of a RF can be separated; (ii) the impulse response can be reconstructed at sample rates of 125 Hz, rather than the refresh rate of a monitor; (iii) FBP reveals the response properties of neurons that are not evident using STA, including those that display orientation selectivity, or fire at low mean spike rates; and (iv) the FBP method is fast, allowing the RFs of all the bipolar cell synaptic terminals in a field of view to be reconstructed in under 4 min. Use of the FBP will benefit investigations of the visual system that employ electrophysiology or optical reporters to measure activity across populations of neurons.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.