ArticleG3 (Bethesda, Md.)2014
Novel X-linked genes revealed by quantitative polymerase chain reaction in the green anole, Anolis carolinensis.
Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 40 citations in OpenAlex.
- Urban Life Shapes Genetic Diversity in the Green Anole, Anolis carolinensis.Molecular ecology · 2025Article
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- A chromosome-level genome assembly for the eastern fence lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology.GigaScience · 2021Article
- Are Geckos Special in Sex Determination? Independently Evolved Differentiated ZZ/ZW Sex Chromosomes in Carphodactylid Geckos.Genome biology and evolution · 2021Article
- Poorly differentiated XX/XY sex chromosomes are widely shared across skink radiation.Proceedings. Biological sciences · 2021Article
- Independent Evolution of Sex Chromosomes in Eublepharid Geckos, A Lineage with Environmental and Genotypic Sex Determination.Life (Basel, Switzerland) · 2020Article
- Do sex chromosomes of snakes, monitor lizards, and iguanian lizards result from multiple fission of an "ancestral amniote super-sex chromosome"?Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2020Article
- Genome Complexity Reduction High-Throughput Genome Sequencing of Green Iguana (Frontiers in genetics · 2020Article
- An Investigation of ZZ/ZW and XX/XY Sex Determination Systems in North African Catfish (Frontiers in genetics · 2020Article
- Deciphering Ancestral Sex Chromosome Turnovers Based on Analysis of Male Mutation Bias.Genome biology and evolution · 2019Article
- Escaping the evolutionary trap? Sex chromosome turnover in basilisks and related lizards (Corytophanidae: Squamata).Biology letters · 2019Article
- Corytophanids Replaced the Pleurodont XY System with a New Pair of XY Chromosomes.Genome biology and evolution · 2019Article
- Article
- Little evidence for switches to environmental sex determination and turnover of sex chromosomes in lacertid lizards.Scientific reports · 2019Article
- Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome.Genome biology and evolution · 2019Article
- Convergent origination of aGenome research · 2017Article
- Evolution of Dosage Compensation in Anolis carolinensis, a Reptile with XX/XY Chromosomal Sex Determination.Genome biology and evolution · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The green anole, Anolis carolinensis (ACA), is the model reptile for a vast array of biological disciplines. It was the first nonavian reptile to have its genome fully sequenced. During the genome project, the XX/XY system of sex chromosomes homologous to chicken chromosome 15 (GGA15) was revealed, and 106 X-linked genes were identified. We selected 38 genes located on eight scaffolds in ACA and having orthologs located on GGA15, then tested their linkage to ACA X chromosome by using comparative quantitative fluorescent real-time polymerase chain reaction applied to male and female genomic DNA. All tested genes appeared to be X-specific and not present on the Y chromosome. Assuming that all genes located on these scaffolds should be localized to the ACA X chromosome, we more than doubled the number of known X-linked genes in ACA, from 106 to 250. While demonstrating that the gene content of chromosome X in ACA and GGA15 is largely conserved, we nevertheless showed that numerous interchromosomal rearrangements had occurred since the splitting of the chicken and anole evolutionary lineages. The presence of many ACA X-specific genes localized to distinct contigs indicates that the ACA Y chromosome should be highly degenerated, having lost a large amount of its original gene content during evolution. The identification of novel genes linked to the X chromosome and absent on the Y chromosome in the model lizard species contributes to ongoing research as to the evolution of sex determination in reptiles and provides important information for future comparative and functional genomics.
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