ArticleGenome biology and evolution2014
Microsporidian genomes harbor a diverse array of transposable elements that demonstrate an ancestry of horizontal exchange with metazoans.
Article in Genome biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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31 citing papers in PubMed, 51 citations in OpenAlex.
- Telomere-to-telomere genome assembly of Microsporidia sp. MB, a microsporidian symbiont of Anopheles coluzzii isolated from Burkina Faso.BMC genomics · 2026Article
- Variation in Genome Architecture and Epigenetic Modification Across the Microsporidia Phylogeny.Genome biology and evolution · 2025Article
- Bioinformatics analysis of the Microsporidia sp. MB genome: a malaria transmission-blocking symbiont of the Anopheles arabiensis mosquito.BMC genomics · 2024Article
- MicroAnnot: A Dedicated Workflow for Accurate Microsporidian Genome Annotation.International journal of molecular sciences · 2024Article
- Near chromosome-level genome assembly of the microsporidium Hamiltosporidium tvaerminnensis.G3 (Bethesda, Md.) · 2023Article
- The intracellular parasite Anncaliia algerae induces a massive miRNA down-regulation in human cells.Non-coding RNA research · 2023Article
- Article
- Population genetic analysis of the microsporidium Ordospora colligata reveals the role of natural selection and phylogeography on its extremely compact and reduced genome.G3 (Bethesda, Md.) · 2023Article
- Genome-Wide Characterization and Comparative Genomic Analysis of the Serpin Gene Family in MicrosporidianInternational journal of molecular sciences · 2022Article
- Impact of Genome Reduction in Microsporidia.Experientia supplementum (2012) · 2022Article
- Microsporidia, a Highly Adaptive Organism and Its Host Expansion to Humans.Frontiers in cellular and infection microbiology · 2022Review
- Comparative Genomics of Microsporidia.Experientia supplementum (2012) · 2022Article
- Distribution of Merlin in eukaryotes and first report of DNA transposons in kinetoplastid protists.PloS one · 2021Article
- A Field Guide to Eukaryotic Transposable Elements.Annual review of genetics · 2020Review
- Evaluating the probability of CRISPR-based gene drive contaminating another species.Evolutionary applications · 2020Article
- The genomic survey of Tc1-like elements in the silkworm microsporidia Nosema bombycis.Acta parasitologica · 2020Article
- Transposable element abundance correlates with mode of transmission in microsporidian parasites.Mobile DNA · 2020Article
- Microsporidia with Vertical Transmission Were Likely Shaped by Nonadaptive Processes.Genome biology and evolution · 2020Article
- Draft Genome Sequence of Tubulinosema ratisbonensis, a Microsporidian Species Infecting the Model Organism Drosophila melanogaster.Microbiology resource announcements · 2019Article
- A genomic survey of transposable elements in the choanoflagellateMobile DNA · 2019Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microsporidian genomes are the leading models to understand the streamlining in response to a pathogenic lifestyle; they are gene-poor and often possess small genomes. In this study, we show a feature of microsporidian genomes that contrasts this pattern of genome reduction. Specifically, genome investigations targeted at Anncaliia algerae, a human pathogen with a genome size of 23 Mb, revealed the presence of a hitherto undetected diversity in transposable elements (TEs). A total of 240 TE families per genome were identified, exceeding that found in many free-living fungi, and searches of microsporidian species revealed that these mobile elements represent a significant portion of their coding repertoire. Their phylogenetic analysis revealed that many cases of ancestry involve recent and bidirectional horizontal transfers with metazoans. The abundance and horizontal transfer origin of microsporidian TEs highlight a novel dimension of genome evolution in these intracellular pathogens, demonstrating that factors beyond reduction are at play in their diversification.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.