ArticleObesity surgery2015
Effect of sleeve gastrectomy on thyroid hormone levels.
Article in Obesity surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Time Trends in Thyroid Hormone Changes Following Bariatric Surgery: A Systematic Review and Meta-Analysis.Obesity surgery · 2026Pooled it
- Thyroid function post-bariatric surgery: an updated systematic review and meta-analysis.Obesity surgery · 2025Pooled it
- Effect of Bariatric Surgery on Thyroid Function in Obese Patients: a Systematic Review and Meta-Analysis.Obesity surgery · 2017Pooled it
- Different impact of sleeve gastrectomy and Roux-en-Y gastric bypass on thyroid function and levothyroxine requirements.Eating and weight disorders : EWD · 2026Observational
- Does Bariatric Surgery Impact Hypothyroidism and Vice Versa? Results of a Prospective Comparative Study.Obesity surgery · 2025Article
- The impact of weight loss interventions on thyroid function: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2025Review
- Metabolic/bariatric surgery optimization: a position statement by Arabic association for the study of diabetes and metabolism (AASD).Diabetology & metabolic syndrome · 2025Review
- Effects of laparoscopic sleeve gastrectomy on thyroid hormones and relationship between metabolic parameters and long-term total weight loss.Surgical endoscopy · 2024Article
- Effect of Laparoscopic Sleeve Gastrectomy on Thyroid Function Tests and Levothyroxine Doses in People With Obesity.Cureus · 2024Article
- Total weight loss induces the alteration in thyroid function after bariatric surgery.Frontiers in endocrinology · 2024Article
- Laparoscopic Sleeve Gastrectomy: Impact on Body Mass Index and Thyroid Hormones in Euthyroid Obese Patients.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- The Impact of Laparoscopic Sleeve Gastrectomy on Thyroid Functions in Egyptian Patients with Obesity.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Article
- Sex dimorphism in the effect and predictors of weight loss after sleeve gastrectomy.Frontiers in endocrinology · 2023Article
- Thyroid Function Before and After Laparoscopic Sleeve Gastrectomy in Patients with Obesity.Obesity surgery · 2022Article
- Effect of Laparoscopic Sleeve Gastrectomy vs. OAGB on Thyroid Function Tests in Patients with Morbid Obesity and Subclinical or Clinical Hypothyroidism.Obesity surgery · 2021Article
- Laparoscopic Sleeve Gastrectomy has A Positive Impact on Subclinical Hypothyroidism Among Obese Patients: A Prospective Study.World journal of surgery · 2021Article
- Thyroid-stimulating hormone and free thyroxine fail to predict the severity and clinical course of hyperemesis gravidarum: A prospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2021Article
- Thyroid Hormone Changes After Sleeve Gastrectomy With and Without Antral Preservation.Obesity surgery · 2021Article
- The advantages and disadvantages of sleeve gastrectomy; clinical laboratory to bedside review.Heliyon · 2020Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWeight loss in morbidly obese patients is associated with changes in thyroid function. Studies have demonstrated equivalent changes following bariatric surgery. Changes in thyroid function were reported following laparoscopic Roux-en-Y gastric bypass (LRYGB), biliopancreatic diversion (BPD), and laparoscopic adjustable gastric banding (LAGB). No data exists on changes in thyroid function following laparoscopic sleeve gastrectomy (LSG). The aim of the current study is to evaluate changes in thyroid function following LSG in patients with normal thyroid function.
methodsData were retrieved from a prospectively collected database of patients who underwent LSG for morbid obesity. Euthyroid patients were evaluated for changes in TSH and free thyroxine (FT4), 6-12 months after surgery. Correlation between changes in thyroid hormone levels, excess weight loss (EWL), and baseline TSH were evaluated.
resultsThirty-eight patients were included in the study. Mean BMI decreased from 42.4 to 32.5 kg/m(2) (P < 0.0001). Mean TSH levels decreased from 2.45 ± 0.17 mU/L at baseline to 1.82 ± 0.18 mU/L (P < 0.0001), whereas mean FT4 levels remained the same after surgery (13.27 ± 0.45 pmol/L compared to 12.96 ± 0.42 pmol/L, P = NS). TSH decrease was directly related to baseline TSH but did not correlate with EWL.
conclusionsThis is the first study to evaluate changes in thyroid hormone levels following LSG for morbid obesity. TSH decrease and steady levels of FT4 are expected following LSG. These findings are comparable to reported changes following LRYGB. TSH decrease was not associated with EWL. Further studies are required to elucidate the exact mechanism of this effect.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.