Evidence map›Paper›PMID 25171662›Full record

Trial reportAmerican journal of physical medicine & rehabilitation2015

Association between lymphedema self-care adherence and lymphedema outcomes among women with breast cancer-related lymphedema.

Justin C Brown, Anagha Kumar, Andrea L Cheville, Julia C Tchou, Andrea B Troxel, Susan R Harris, Kathryn H Schmitz

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of physical medicine & rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Observational
  7. Article
  8. Lymphedema self-care: economic cost savings and opportunities to improve adherence.Cost effectiveness and resource allocation : C/E · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Development and validation of the Lymphedema Symptom and Intensity Survey-Arm.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Justin C BrownFrom the University of Pennsylvania, Philadelphia, Pennsylvania (JCB, AK, JCT, ABT, KHS); Mayo Clinic, Rochester, Minnesota (ALC); and University of British Columbia, Vancouver, British Columbia, Canada (SRH).
Anagha Kumar
Andrea L Cheville
Julia C Tchou
Andrea B Troxel
Susan R Harris
Kathryn H Schmitz
St. Raphael's Hospital · PKALK-Abelló (Germany) · DE

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Robert H. Vonderheide · 1985 to 2026
$222.3M
Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
The Women In Steady Exercise Research (WISER) SurwVor TrialU54CA155850 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHODOSH, LEWIS A · 2011 to 2015
$9.1M
Physical Activity and Lymphedema Project (PAL Trial)R01CA106851 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SCHMITZ, KATHRYN H. · 2004 to 2007
$2.2M
NCATS NIH HHS UL1 TR000135NCI NIH HHS P30 CA016520NCI NIH HHS R01 CA106851NCI NIH HHS U54 CA155850
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine whether adherence to self-care modalities for breast cancer-related lymphedema (BCRL) predicts BCRL outcomes among 128 breast cancer survivors who participated in the 12-mo physical activity and lymphedema trial.

designThis was a prospective cohort study. Adherence to ten BCRL self-care modalities, as recommended in the clinical practice guidelines for the management of BCRL, was assessed by a questionnaire at baseline. BCRL outcomes assessed at baseline and 12 mos included volumetry, circumferences, bioimpedence spectroscopy, the Norman lymphedema survey, and therapist-defined lymphedema exacerbations requiring treatment. Generalized linear models were used to estimate the relationship between adherence to BCRL self-care modalities and the likelihood of experiencing a BCRL outcome.

resultsAdherence to BCRL self-care activities did not predict experiencing any BCRL outcomes at 12 mos. Levels of adherence to BCRL self-care modalities did not predict a 5% or greater decrease in interlimb volume (Ptrend = 0.79), 5% or greater decrease in the sum of interlimb arm circumferences (Ptrend = 0.47), 10% or greater decrease in bioimpedence spectroscopy (Ptrend = 0.83), 1 or greater decrease in self-reported lymphedema symptoms (Ptrend = 0.91), or therapist-defined lymphedema exacerbation requiring treatment (Ptrend = 0.84).

conclusionsOur findings suggest that levels of BCRL self-care adherence do not predict BCRL outcomes among breast cancer survivors with stable lymphedema who were followed for 12 mos.

Indexed as

Patient ComplianceSelf CareWeight LiftingAgedBreast NeoplasmsFemaleHumansLinear ModelsLymphedemaMiddle AgedPostoperative ComplicationsProspective StudiesTreatment Outcome

Identifiers

PMID25171662
PMCPMC4344918
OpenAlexW2110610579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.