Evidence map›Paper›PMID 25171642›Full record

ReviewInternational ophthalmology clinics2014

Consideration for gene-environment interactions as novel determinants of exfoliation syndrome.

Louis R Pasquale, Jae H Kang, Janey L Wiggs

Abstract readReview
In one paragraph

Review in International ophthalmology clinics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Clusterin, other extracellular chaperones, and eye disease.Progress in retinal and eye research · 2022
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louis R Pasquale
Jae H Kang
Janey L Wiggs

Funding

Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2000 to 2019
$77.8M
Gene-Environment Interactions in GlaucomaR01EY015473 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI PASQUALE, LOUIS ROBERT · 2005 to 2021
$8.3M
Genetic and Environmental Risk Factors for Exfoliation Syndrome and GlaucomaR01EY020928 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI KANG, JAE H, WIGGS, JANEY L · 2011 to 2025
$7.3M
PROSPECTIVE STUDY OF RISK FACTORS FOR EYE DISEASER01EY009611 · NEI · BRIGHAM AND WOMEN'S HOSPITAL · PI HANKINSON, SUSAN E. · 1995 to 2004
$2.2M
NCI NIH HHS CA87969NCI NIH HHS P01 CA087969NEI NIH HHS EY015473NEI NIH HHS EY020928NEI NIH HHS EY09611NEI NIH HHS R01 EY009611NEI NIH HHS R01 EY015473NEI NIH HHS R01 EY020928
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene-Environment InteractionAmino Acid OxidoreductasesClimateDietExfoliation SyndromeGenetic Predisposition to DiseaseHumansRisk FactorsUltraviolet RaysAmino Acid OxidoreductasesLOXL1 protein, human

Identifiers

PMID25171642
PMCPMC4155760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.