ArticlePloS one2014
Variability of the pharyngeal phase of swallow in the cat.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Research advances in dysphagia animal models.Animal models and experimental medicine · 2025Review
- Serotonin therapies for opioid-induced disordered swallow and respiratory depression.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Evidence for peripheral and central actions of codeine to dysregulate swallowing in the anesthetized cat.Frontiers in neurology · 2024Article
- Deglutition and the Regulation of the Swallow Motor Pattern.Physiology (Bethesda, Md.) · 2023 · on this mapReview
- Incidence, clinical signs, and videofluoroscopic swallow study abnormalities associated with airway penetration and aspiration in 100 dogs.Journal of veterinary internal medicine · 2022Article
- Laryngeal and swallow dysregulation following acute cervical spinal cord injury.Journal of neurophysiology · 2022Article
- Evidence of intermediate reticular formation involvement in swallow pattern generation, recorded optically in the neonate rat sagittally sectioned hindbrain.Journal of neurophysiology · 2021Article
- Article
- Adaptations to Oral and Pharyngeal Swallowing Function Induced by Injury to the Mylohyoid Muscle.Dysphagia · 2020Article
- Swallow Motor Pattern Is Modulated by Fixed or Stochastic Alterations in Afferent Feedback.Frontiers in human neuroscience · 2020Article
- Sex-specific vagal and spinal modulation of swallow and its coordination with breathing.PloS one · 2020Article
- Neurons in the dorsomedial medulla contribute to swallow pattern generation: Evidence of inspiratory activity during swallow.PloS one · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveThe pharyngeal phase of swallow has been thought to be a stereotypical motor behavior. STUDY
designThis is a prospective, preclinical, hypothesis driven, one group by three-task design.
methodsWe sought to compare the effects of pharyngeal swabbing, water only, and water plus punctate mechanical stimulation on the spatiotemporal features of the pharyngeal phase of swallow in the cat. Swallow was elicited under these three conditions in six anaesthetized cats. Electromyographic activity was recorded from seven muscles used to evaluate swallow: mylohyoid, geniohyoid, thyrohyoid, thyroarytenoid, thyropharyngeus, cricopharyngeus, and parasternal.
resultsPharyngeal swabbing in comparison to the other stimulus conditions, results in decreases in post-swallow cricopharyngeus activity (upper esophageal sphincter); a significant increase in parasternal (schluckatmung; swallow breath) activity; and increases in thyrohyoid (laryngeal elevator), thyroarytenoid (laryngeal adductor) and parasternal muscles burst duration. Pearson correlations were found of moderate strength between 19% of burst duration comparisons and weak to moderate relationships between 29% of burst amplitude comparisons. However, there were no positive significant relationships between phase durations and electromyogram amplitudes between any of the muscles studied during swallow.
conclusionsThe results support the concept that a stereotypical behavior, such as pharyngeal swallowing in animal models, can be modified by sensory feedback from pharyngeal mucosal mechanoreceptors. Furthermore, differences in swallow phase durations and amplitudes provide evidence that separate regulatory mechanisms exist which regulate spatial and temporal aspects of the behavior.
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