Evidence map›Paper›PMID 25170192›Full record

ReviewWorld journal of gastroenterology2014

Non-pulmonary allergic diseases and inflammatory bowel disease: a qualitative review.

David S Kotlyar, Mili Shum, Jennifer Hsieh, Wojciech Blonski, David A Greenwald

Open access · hybridAbstract readEditorialReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David S KotlyarDavid S Kotlyar, Medical Oncology Service, NIH National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Mili ShumDavid S Kotlyar, Medical Oncology Service, NIH National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Jennifer HsiehDavid S Kotlyar, Medical Oncology Service, NIH National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Wojciech BlonskiDavid S Kotlyar, Medical Oncology Service, NIH National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
David A GreenwaldDavid S Kotlyar, Medical Oncology Service, NIH National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
National Institutes of Health · US

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

While the etiological underpinnings of inflammatory bowel disease (IBD) are highly complex, it has been noted that both clinical and pathophysiological similarities exist between IBD and both asthma and non-pulmonary allergic phenomena. In this review, several key points on common biomarkers, pathophysiology, clinical manifestations and nutritional and probiotic interventions for both IBD and non-pulmonary allergic diseases are discussed. Histamine and mast cell activity show common behaviors in both IBD and in certain allergic disorders. IgE also represents a key immunoglobulin involved in both IBD and in certain allergic pathologies, though these links require further study. Probiotics remain a critically important intervention for both IBD subtypes as well as multiple allergic phenomena. Linked clinical phenomena, especially sinonasal disease and IBD, are discussed. In addition, nutritional interventions remain an underutilized and promising therapy for modification of both allergic disorders and IBD. Recommending new mothers breastfeed their infants, and increasing the duration of breastfeeding may also help prevent both IBD and allergic diseases, but requires more investigation. While much remains to be discovered, it is clear that non-pulmonary allergic phenomena are connected to IBD in a myriad number of ways and that the discovery of common immunological pathways may usher in an era of vastly improved treatments for patients.

Indexed as

HypersensitivityInflammatory Bowel DiseasesIntestinesAnimalsBiomarkersHumansInflammation MediatorsNutritional StatusProbioticsPrognosisRisk FactorsBiomarkersInflammation MediatorsBiomarkersCrohn’s diseaseFood allergiesFood intoleranceInflammatory bowel diseaseNutritionPathophysiologyProbioticsUlcerative colitis

Identifiers

PMID25170192
PMCPMC4145746
OpenAlexW1980694952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.