Evidence map›Paper›PMID 25170184›Full record

ArticleThe American journal of occupational therapy : official publication of the American Occupational Therapy Association2011

Prenatal Cocaine Exposure and Motor Performance at 4 Months.

Rosemarie Bigsby, Linda L LaGasse, Barry Lester, Seetha Shankaran, Henrietta Bada, Charles Bauer, Jing Liu

Abstract read
In one paragraph

Article in The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Developmental consequences of fetal exposure to drugs: what we know and what we still must learn.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
    Review
  3. Psychostimulants and movement disorders.Frontiers in neurology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rosemarie BigsbyClinical Associate Professor of Pediatrics and Clinical Associate Professor of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University and The Brown Center for the Study of Children At Risk, Women and Infants' Hospital, 101 Dudley Street, Providence, RI 02748.
Linda L LaGasseAssociate Professor of Pediatrics and Associate Professor of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University and The Brown Center for the Study of Children At Risk, Providence, RI.
Barry LesterProfessor of Pediatrics and Professor of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University and The Brown Center for the Study of Children At Risk, Providence, RI.
Seetha ShankaranProfessor of Pediatrics, Wayne State University School of Medicine, Detroit, MI.
Henrietta BadaProfessor of Pediatrics, University of Kentucky Medical School, Lexington.
Charles BauerProfessor of Pediatrics, University of Miami Medical School, Miami, FL.
Jing LiuSenior Study Director, Westat, Inc., Rockville, MD.

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkU10HD021385 · NICHD · WAYNE STATE UNIVERSITY · PI SHANKARAN, SEETHA · 1991 to 2015
$8.7M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027904 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LAPTOOK, ABBOT R · 1991 to 2015
$8.7M
MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITSU10HD021397 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DUARA, SHAHNAZ · 1991 to 2006
$6.7M
Maternal Lifestyle Study Phase 5U10DA024119 · NIDA · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LESTER, BARRY M. · 2007 to 2011
$4.4M
NEURODEVELOPMENT OF INFANTS EXPOSED TO DRUGS IN-UTERON01HD023159 · NICHD · EMMA PENDLETON BRADLEY HOSPITAL · PI LESTER, BARRY M. · 1992 to 2000
$385k
NICHD NIH HHS N01 HD023159NICHD NIH HHS U10 HD021385NICHD NIH HHS U10 HD021397NICHD NIH HHS U10 HD027904NIDA NIH HHS U10 DA024119
6 · The paper itself

Abstract

objectiveThe relation between prenatal cocaine exposure and quality of movement was studied at 4 mo using the Posture and Fine Motor Assessment of Infants (PFMAI-I).

methodPosture and fine motor scores of 4-month-old infants exposed to cocaine in utero (

resultsInfants prenatally exposed to cocaine had significantly lower posture scores than infants in the unexposed group. There was no main effect of cocaine exposure on fine motor scores; however, there were independent effects of gestational age at birth on both posture and fine motor scores at 4-mo corrected age.

conclusionThese findings demonstrate independent contributions of prenatal cocaine exposure and prematurity to risk of motor delay and support the validity of the PFMAI-I as a measure of motor competence in early infancy.

Indexed as

child developmentcocaine-related disordersmotor skillspostureprenatal exposure delayed effects

Identifiers

PMID25170184
PMCPMC4144172

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.