ArticleScience (New York, N.Y.)2014
Thyroid hormone-dependent adult pigment cell lineage and pattern in zebrafish.
Article in Science (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
115 citing papers in PubMed, 247 citations in OpenAlex.
- Ambient Developmental Temperatures and Maternal Thyroid Supply Promote Early Life Diversification in Salmonids.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026Article
- Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration.bioRxiv : the preprint server for biology · 2026Article
- Loss of MITF activity leads to emergent cell states from the melanocyte stem cell lineage.bioRxiv : the preprint server for biology · 2026Article
- A potential cis-regulatory element regulates differential expression of long wavelength-sensitive opsins in zebrafish.Scientific reports · 2026Article
- Cell type diversification and phenotype convergence underlying white fin-ornamentation of cyprinid fishes.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Hypothyroidism as Prognostic Factor in Cutaneous Melanoma: A 1553-Patient Single-Center Study.Cancer medicine · 2026Article
- Genomic and genetic insights into speciation and pigment pattern diversification inbioRxiv : the preprint server for biology · 2025Article
- Dominant Negative Mitf Allele Impacts Melanophore and Xanthophore Development and Reveals Collaborative Interactions With Tfec in Zebrafish Chromatophore Lineages.Pigment cell & melanoma research · 2025Article
- The hybrid history of zebrafish.G3 (Bethesda, Md.) · 2025Article
- Functions of thyroid hormone signaling in regulating melanophore, iridophore, erythrophore, and pigment pattern formation in spotted scat (Scatophagus argus).BMC genomics · 2025Article
- Sox10 is required for systemic initiation of bone mineralization.Development (Cambridge, England) · 2025Article
- Thyroid hormone receptor beta-2 (TRβ2) overexpression modulates photoreceptor phenotype diversity in a ligand-dependent manner.Frontiers in cell and developmental biology · 2025Article
- Experimentally Manipulating the Thyroid Hormone Axis in Zebrafish.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Growth patterns of caudal fin rays are informed by both external signals from the regenerating organ and remembered identity autonomous to the local tissue.Developmental biology · 2024Article
- Phylogenomic analysis of the Lake Kronotskoe species flock of Dolly Varden charr reveals genetic and developmental signatures of sympatric radiation.Development (Cambridge, England) · 2024Article
- Assessing the effects of fluorine-free and PFAS-containing firefighting foams on development and behavioral responses using a zebrafish-based platform.Chemosphere · 2024Article
- The transcriptional landscape underlying larval development and metamorphosis in the Malabar grouper (eLife · 2024Article
- Melanocyte lineage dynamics in development, growth and disease.Development (Cambridge, England) · 2024Review
- Whole-body replacement of larval myofibers generates permanent adult myofibers in zebrafish.The EMBO journal · 2024Article
- The dynamic behavior of chromatophores marks the transition from bands to spots in leopard geckos.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Pigment patterns are useful for elucidating fundamental mechanisms of pattern formation and how these mechanisms evolve. In zebrafish, several pigment cell classes interact to generate stripes, yet the developmental requirements and origins of these cells remain poorly understood. Using zebrafish and a related species, we identified roles for thyroid hormone (TH) in pigment cell development and patterning, and in postembryonic development more generally. We show that adult pigment cells arise from distinct lineages having distinct requirements for TH and that differential TH dependence can evolve within lineages. Our findings demonstrate critical functions for TH in determining pigment pattern phenotype and highlight the potential for evolutionary diversification at the intersection of developmental and endocrine mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.