Evidence map›Paper›PMID 25169882›Full record

ArticleThe journal of headache and pain2014

Refractory chronic migraine: a consensus statement on clinical definition from the European Headache Federation.

Paolo Martelletti, Zaza Katsarava, Christian Lampl, Delphine Magis, Lars Bendtsen, Andrea Negro, Michael Bjørn Russell, Dimos-Dimitrios D Mitsikostas, Rigmor Højland Jensen

Abstract readConsensus Statement
In one paragraph

Article in The journal of headache and pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Trial
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  6. Single-blind, randomized, pilot study combining shiatsu and amitriptyline in refractory primary headaches.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
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  17. Therapeutic effect of memantine on patients with posttraumatic headache: A randomized double-blinded clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Article
  18. Article
  19. Long term outcomes of occipital nerve stimulation.Frontiers in pain research (Lausanne, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Paolo MartellettiDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy. paolo.martelletti@uniroma1.it.
Zaza Katsarava
Christian Lampl
Delphine Magis
Lars Bendtsen
Andrea Negro
Michael Bjørn Russell
Dimos-Dimitrios D Mitsikostas
Rigmor Højland Jensen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The debate on the clinical definition of refractory Chronic Migraine (rCM) is still far to be concluded. The importance to create a clinical framing of these rCM patients resides in the complete disability they show, in the high risk of serious adverse events from acute and preventative drugs and in the uncontrolled application of therapeutic techniques not yet validated.The European Headache Federation Expert Group on rCM presents hereby the updated definition criteria for this harmful subset of headache disorders. This attempt wants to be the first impulse towards the correct identification of these patients, the correct application of innovative therapeutic techniques and lastly aim to be acknowledged as clinical entity in the next definitive version of the International Classification of Headache Disorders 3 (ICHD-3 beta).

Indexed as

ConsensusChronic DiseaseEuropeHumansMigraine DisordersVoluntary Health Agencies

Identifiers

PMID25169882
PMCPMC4237793

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.