Evidence map›Paper›PMID 25169560›Full record

ReviewEndocrinology and metabolism clinics of North America2014

Dyslipidemia and cardiovascular risk in human immunodeficiency virus infection.

Theodoros Kelesidis, Judith S Currier

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03470376 (Lipid-lowering and Vascular Effects of a Nutraceutical Combination in HIV-infected Patients on Stable Antiretroviral Therapy), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03470376 phase4completednot on this mapstarted 2017, after this paper: background citation

Lipid-lowering and Vascular Effects of a Nutraceutical Combination in HIV-infected Patients on Stable Antiretroviral Therapy

TypeinterventionalSponsorUniversity Of PerugiaRan2017 to 2017Enrolled26ConditionsHypercholesterolemia, Inflammation, AtherosclerosisArmsNutraceutical combination (NC), No nutraceutical combination (noNC)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Recent advances in CD8Heliyon · 2023
    Review
  9. Cardiovascular Disease and Thrombosis in HIV Infection.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Changes in Lipid Indices in HIV+ Cases on HAART.BioMed research international · 2019
    Article
  14. Article
  15. Article
  16. Observational
  17. Observational
  18. Review
  19. Article
  20. Predictors of Impaired HDL Function in HIV-1 Infected Compared to Uninfected Individuals.Journal of acquired immune deficiency syndromes (1999) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Theodoros KelesidisDivision of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, UCLA, 9911 W. Pico Boulevard, Suite 980, Los Angeles, CA 90035, USA.
Judith S CurrierDivision of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, UCLA, 9911 W. Pico Boulevard, Suite 980, Los Angeles, CA 90035, USA. Electronic address: jscurrier@mednet.ucla.edu.
University of California, Los Angeles · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Oxidized HDL in the intersection of HIV, immune activation and atherosclerosisK08AI108272 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS · 2013 to 2017
$915k
NCATS NIH HHS UL1 TR000124NIAID NIH HHS K08 AI108272
6 · The paper itself

Abstract

The pathogenesis of atherosclerosis in human immunodeficiency virus (HIV)-infected individuals is incompletely understood and appears to be multifactorial. Proatherogenic changes in blood and tissue lipids are associated with an increased risk of cardiovascular disease among HIV-infected subjects, and these changes may be both quantitative (dyslipidemia) and qualitative. In view of the pivotal role of dyslipidemia in the process of atherosclerosis, the increased incidence of dyslipidemia in HIV-infected individuals, and the emerging role of lipid abnormalities in systemic pathophysiologic processes such as immune activation, we review the contributions of dyslipidemia to cardiovascular risk in HIV infection.

Indexed as

Cardiovascular DiseasesDyslipidemiasHIV-1HIV InfectionsHost-Pathogen InteractionsHumansLipid MetabolismRisk FactorsAntiretroviral therapyCardiovascular riskDyslipidemiaHuman immunodeficiency virus

Identifiers

PMID25169560
PMCPMC5054418
OpenAlexW2055111878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.