ReviewCurrent osteoporosis reports2014
Imaging of site specific bone turnover in osteoporosis using positron emission tomography.
Review in Current osteoporosis reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 35 citations in OpenAlex.
- Influence of Hydroxyapatite Coating for the Prevention of Bone Mineral Density Loss and Bone Metabolism after Total Hip Arthroplasty: Assessment UsingBioMed research international · 2020Trial
- The emerging role of ¹⁸F-NaF PET/CT in osteoporosis: an emphasis on its application for the evaluation and management of lumbar spine osteoporosis.EJNMMI research · 2026Review
- Measuring bone metabolic activity in dialysis patients with renal osteodystrophy using [BMC nephrology · 2025Article
- Emerging Role ofPET clinics · 2023Review
- Association between bone mineral metabolism and vascular calcification in end-stage renal disease.BMC nephrology · 2022Article
- Bone Histomorphometry andCalcified tissue international · 2021Article
- Article
- Assessment of quantitative [Osteoarthritis and cartilage · 2021Article
- Total-Body PET Imaging of Musculoskeletal Disorders.PET clinics · 2021Review
- Multiplexed Molecular Imaging Strategy Integrated with RNA Sequencing in the Assessment of the Therapeutic Effect of Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles for Osteoporosis.International journal of nanomedicine · 2021Article
- Comparison ofEuropean journal of nuclear medicine and molecular imaging · 2020Article
- Reinventing Molecular Imaging with Total-Body PET, Part II: Clinical Applications.PET clinics · 2020Review
- Association of Regional Bone Synthetic Activities of Vertebral Corners and Vertebral Bodies Quantified UsingJournal of clinical medicine · 2020Article
- Article
- Assessment of acute bone loading in humans using [European journal of nuclear medicine and molecular imaging · 2019Article
- Kinetic [18F]-Fluoride of the Knee in Normal Volunteers.Clinical nuclear medicine · 2019Article
- PET-MRI for the Study of Metabolic Bone Disease.Current osteoporosis reports · 2018Review
- Clinical Nononcologic Applications of PET/CT and PET/MRI in Musculoskeletal, Orthopedic, and Rheumatologic Imaging.AJR. American journal of roentgenology · 2018Review
- Vertebral Imaging in the Diagnosis of Osteoporosis: a Clinician's Perspective.Current osteoporosis reports · 2017Review
- [Progress of quantitative measurement of bone usingSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The functional imaging technique of dynamic fluorine-18 labeled sodium fluoride positron emission tomography ((18)F-NaF PET) allows the quantitative assessment of regional bone formation by measuring the plasma clearance of fluoride to bone at any site in the skeleton. (18)F-NaF PET provides a novel and noninvasive method of studying site-specific bone formation at the hip and spine, as well as areas of pure cortical or trabecular bone. The technique complements conventional measurements of bone turnover using biochemical markers and bone biopsy as a tool to investigate new treatments for osteoporosis, and holds promise of a future role as an early biomarker of treatment efficacy in clinical trials. This article reviews methods of acquiring and analyzing (18)F-NaF PET scan data, and outlines a simplified approach that uses 5-minute static PET scan images combined with venous blood samples to estimate (18)F-NaF plasma clearance at multiple sites in the skeleton with a single injection of tracer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.