ReviewDrug discovery today2014
PubChem applications in drug discovery: a bibliometric analysis.
Review in Drug discovery today, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dyslexia: A Bibliometric and Visualization Analysis.Frontiers in public health · 2022Pooled it
- The Road to Precision Nanomedicine: An Insight on Drug Repurposing and Advances in Nanoformulations for Treatment of Cancer.AAPS PharmSciTech · 2025Review
- Article
- Computational Network Pharmacology, Molecular Docking, and Molecular Dynamics to Decipher Natural Compounds ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Article
- Quantum Chemistry Dataset with Ground- and Excited-state Properties of 450 Kilo Molecules.Scientific data · 2024Article
- Article
- Integrating network pharmacology with molecular docking to rationalize the ethnomedicinal use ofFrontiers in pharmacology · 2024Article
- Structure-based identification of novel inhibitors targeting the enoyl-ACP reductase enzyme of Acinetobacter baumannii.Scientific reports · 2023Article
- Article
- Computational identification of potential inhibitors targetingFrontiers in chemistry · 2023Article
- Emerging insights into inflammatory bowel disease from the intestinal microbiota perspective: a bibliometric analysis.Frontiers in immunology · 2023Review
- Highly potent natural fungicides identified in silico against the cereal killer fungus Magnaporthe oryzae.Scientific reports · 2022Article
- Hybrid Approach to Identifying Druglikeness Leading Compounds against COVID-19 3CL Protease.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Benchmarking Data Sets from PubChem BioAssay Data: Current Scenario and Room for Improvement.International journal of molecular sciences · 2020Review
- Applications of Network Pharmacology in Traditional Chinese Medicine Research.Evidence-based complementary and alternative medicine : eCAM · 2020Review
- CMAUP: a database of collective molecular activities of useful plants.Nucleic acids research · 2019Article
- A Proteotranscriptomic-Based Computational Drug-Repositioning Method for Alzheimer's Disease.Frontiers in pharmacology · 2019Article
- Documenting and harnessing the biological potential of molecules in Distributed Drug Discovery (D3) virtual catalogs.Chemical biology & drug design · 2017Article
- PubChem BioAssay: A Decade's Development toward Open High-Throughput Screening Data Sharing.SLAS discovery : advancing life sciences R & D · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A bibliometric analysis of PubChem applications is presented by reviewing 1132 research articles. The massive volume of chemical structure and bioactivity data in PubChem and its online services have been used globally in various fields including chemical biology, medicinal chemistry and informatics research. PubChem supports drug discovery in many aspects such as lead identification and optimization, compound-target profiling, polypharmacology studies and unknown chemical identity elucidation. PubChem has also become a valuable resource for developing secondary databases, informatics tools and web services. The growing PubChem resource with its public availability offers support and great opportunities for the interrogation of pharmacological mechanisms and the genetic basis of diseases, which are vital for drug innovation and repurposing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.