ReviewTrends in genetics : TIG2014
Toward a new history and geography of human genes informed by ancient DNA.
Review in Trends in genetics : TIG, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spatiotemporal fluctuations of population structure in the Americas revealed by a meta-analysis of the first decade of archaeogenomes.American journal of biological anthropology · 2023Pooled it
- Ancient DNA as a temporal lens: reconstructing evolution, migration, and disease dynamics.Journal, genetic engineering & biotechnology · 2026Review
- ROLE OF POLYMORPHISMS IN VEGF AND KDR GENES IN OSTEOSARCOMA SUSCEPTIBILITY: A SYSTEMATIC REVIEW.Acta ortopedica brasileira · 2025Review
- The genomic footprints of migration: how ancient DNA reveals our history of mobility.Genome biology · 2025Review
- Wild or Introduced? Investigating the Genetic Landscape of Cacao Populations in South America.Ecology and evolution · 2025Article
- Association of the IL-10 and IL-18 polymorphisms with nasopharyngeal carcinoma risk.Frontiers in oncology · 2025Article
- Elucidating genetic variability between randomly bred domestic cats and Persian domestic cats from different geographical locations using microsatellite markers.Veterinary medicine and science · 2024Article
- Global and Local Ancestry and its Importance: A Review.Current genomics · 2024Review
- Haplotype-based inference of recent effective population size in modern and ancient DNA samples.Nature communications · 2023Article
- Methods for Assessing Population Relationships and History Using Genomic Data.Annual review of genomics and human genetics · 2023Review
- Advancements and Challenges in Ancient DNA Research: Bridging the Global North-South Divide.Genes · 2023Review
- Article
- Patterns of variation in canal and root number in human post-canine teeth.Journal of anatomy · 2022Article
- Review
- The apportionment of citations: a scientometric analysis of Lewontin 1972.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- A geometric relationship ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- The spatiotemporal patterns of major human admixture events during the European Holocene.eLife · 2022Article
- Evidence for serial founder events during the colonization of North America by the yellow fever mosquito,Ecology and evolution · 2022Article
- The genomic signatures of natural selection in admixed human populations.American journal of human genetics · 2022Article
- Health equality, race and pharmacogenomics.British journal of clinical pharmacology · 2022Review
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Genetic information contains a record of the history of our species, and technological advances have transformed our ability to access this record. Many studies have used genome-wide data from populations today to learn about the peopling of the globe and subsequent adaptation to local conditions. Implicit in this research is the assumption that the geographic locations of people today are informative about the geographic locations of their ancestors in the distant past. However, it is now clear that long-range migration, admixture, and population replacement subsequent to the initial out-of-Africa expansion have altered the genetic structure of most of the world's human populations. In light of this we argue that it is time to critically reevaluate current models of the peopling of the globe, as well as the importance of natural selection in determining the geographic distribution of phenotypes. We specifically highlight the transformative potential of ancient DNA. By accessing the genetic make-up of populations living at archaeologically known times and places, ancient DNA makes it possible to directly track migrations and responses to natural selection.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.