ArticleEnvironmental science and pollution research international2015
Antibiotic resistance and prevalence of class 1 and 2 integrons in Escherichia coli isolated from two wastewater treatment plants, and their receiving waters (Gulf of Gdansk, Baltic Sea, Poland).
Article in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 106 citations in OpenAlex.
- Biodiversity of Genetic, Metabolic, and Antibiotic Resistance Profiles ofMicroorganisms · 2026Article
- Genomic insights into multidrug resistance in clinicalFrontiers in microbiology · 2026Article
- Heavy Metals and Carbapenem-Resistant Klebsiella pneumoniae in a River System of Odisha, India: Correlation and Integrated Risk Assessment.Microbial ecology · 2025Article
- The Impact of Wastewater on Antimicrobial Resistance: A Scoping Review of Transmission Pathways and Contributing Factors.Antibiotics (Basel, Switzerland) · 2025Review
- Modeling solutions for microbial water contamination in the global south for public health protection.Frontiers in microbiology · 2025Review
- Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes.FEMS microbiology reviews · 2024Review
- Antimicrobial resistance in food-associatedBioscience of microbiota, food and health · 2024Review
- Biofilms as Battlefield Armor for Bacteria against Antibiotics: Challenges and Combating Strategies.Microorganisms · 2023Review
- Wastewater treatment plants, an "escape gate" for ESCAPE pathogens.Frontiers in microbiology · 2023Review
- Clinically Relevant β-Lactam Resistance Genes in Wastewater Treatment Plants.International journal of environmental research and public health · 2022Review
- Occurrence of Antimicrobial-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- High Rates of Multidrug-ResistantPathogens (Basel, Switzerland) · 2022Article
- Discarded masks as hotspots of antibiotic resistance genes during COVID-19 pandemic.Journal of hazardous materials · 2022Article
- Existing evidence on antibiotic resistance exposure and transmission to humans from the environment: a systematic map.Environmental evidence · 2022Article
- Carriage of ESBL-producing Enterobacterales in wastewater treatment plant workers and surrounding residents - the AWARE Study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Ultrafiltration Process in Disinfection and Advanced Treatment of Tertiary Treated Wastewater.Membranes · 2021Article
- Molecular Characterization of Class 1, 2 and 3 Integrons inInfection and drug resistance · 2021Article
- Azole antifungal resistance in fungal isolates from wastewater treatment plant effluents.Environmental science and pollution research international · 2021Article
- Markers Specific toInternational journal of environmental research and public health · 2020Article
- Evolution of antibiotic resistance at low antibiotic concentrations including selection below the minimal selective concentration.Communications biology · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, antimicrobial-resistance patterns were analyzed in Escherichia coli isolates from raw (RW) and treated wastewater (TW) of two wastewater treatment plants (WWTPs), their marine outfalls (MOut), and mouth of the Vistula River (VR). Susceptibility of E. coli was tested against different classes of antibiotics. Isolates resistant to at least one antimicrobial agent were PCR tested for the presence of integrons. Ampicillin-resistant E. coli were the most frequent, followed by amoxicillin/clavulanate (up to 32 %), trimethoprim/sulfamethoxazole (up to 20 %), and fluoroquinolone (up to 15 %)-resistant isolates. Presence of class 1 and 2 integrons was detected among tested E. coli isolates with rate of 32.06 % (n = 84) and 3.05 % (n = 8), respectively. The presence of integrons was associated with increased frequency of resistance to fluoroquinolones, trimethoprim/sulfamethoxazole, amoxicillin/clavulanate, piperacillin/tazobactam, and presence of multidrug-resistance phenotype. Variable regions were detected in 48 class 1 and 5 class 2 integron-positive isolates. Nine different gene cassette arrays were confirmed among sequenced variable regions, with predominance of dfrA1-aadA1, dfrA17-aadA5, and aadA1 arrays. These findings illustrate the importance of WWTPs in spreading of resistance genes in the environment and the need for inclusion of at least monitoring efforts in the regular WWTP processes.
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