ReviewTrends in neurosciences2014
Preserve and protect: maintaining axons within functional circuits.
Review in Trends in neurosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Genes in Axonal Regeneration.Molecular neurobiology · 2024Review
- Immunocytochemical Analysis of Crocin against Oxidative Stress in Trigeminal Sensory Neurons Innervating the Cornea.Molecules (Basel, Switzerland) · 2024Article
- Local glycolysis fuels actomyosin contraction during axonal retraction.The Journal of cell biology · 2023Article
- Brain Trauma and the Secondary Cascade in Humans: Review of the Potential Role of Vitamins in Reparative Processes and Functional Outcome.Behavioral sciences (Basel, Switzerland) · 2023Review
- Dendritic Spines: Synaptogenesis and Synaptic Pruning for the Developmental Organization of Brain Circuits.Advances in neurobiology · 2023Article
- Article
- Axonal mRNA translation in neurological disorders.RNA biology · 2021Review
- Building a (w)rapport between neurons and oligodendroglia: Reciprocal interactions underlying adaptive myelination.Neuron · 2021Review
- Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing.Cell death and differentiation · 2020Article
- Calcium, Bioenergetics, and Parkinson's Disease.Cells · 2020Review
- Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program.JCI insight · 2019Article
- Review
- Phosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration.Cell death & disease · 2018Article
- Axonal Mitochondria Modulate Neuropeptide Secretion Through the Hypoxic Stress Response inGenetics · 2018Article
- Paclitaxel Reduces Axonal Bclw to Initiate IPNeuron · 2017Article
- Roles of palmitoylation in axon growth, degeneration and regeneration.Journal of neuroscience research · 2017Review
- Accumulating Evidence for Axonal Translation in Neuronal Homeostasis.Frontiers in neuroscience · 2017Review
- Axon degeneration: context defines distinct pathways.Current opinion in neurobiology · 2016Review
- Tumor protein Tctp regulates axon development in the embryonic visual system.Development (Cambridge, England) · 2016Article
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
During development, neural circuits are initially generated by exuberant innervation and are rapidly refined by selective preservation and elimination of axons. The establishment and maintenance of functional circuits therefore requires coordination of axon survival and degeneration pathways. Both developing and mature circuits rely on interdependent mitochondrial and cytoskeletal components to maintain axonal health and homeostasis; injury or diseases that impinge on these components frequently cause pathologic axon loss. Here, we review recent findings that identify mechanisms of axonal preservation in the contexts of development, injury, and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.