Evidence map›Paper›PMID 25167081›Full record

ArticleChest2014

Nurse practitioner/physician assistant staffing and critical care mortality.

Deena Kelly Costa, David J Wallace, Amber E Barnato, Jeremy M Kahn

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Chest, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 102 citations in OpenAlex.

  1. Availability of Advanced Practice Providers in Adult Intensive Care Units in the United States: A Survey.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2025
    Article
  2. Article
  3. Interprofessional Team Staffing in U.S. Intensive Care Units.Annals of the American Thoracic Society · 2025
    Article
  4. [Academised nursing in direct patient care-but how?]Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024
    Review
  5. Article
  6. Article
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  8. Article
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  10. Review
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  15. Article
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  18. Differences between nurse- and physician-assessed ICU characteristics using a standardized survey.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2015
    Article
  19. Teamwork in the intensive care unit.The American psychologist
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Deena Kelly CostaClinical Research, Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA.
David J WallaceClinical Research, Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA; Department of Emergency Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA.
Amber E BarnatoDivision of General Internal Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA.
Jeremy M KahnClinical Research, Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA; University of Pittsburgh School of Medicine; and Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA. Electronic address: kahnjm@upmc.edu.
University of Pittsburgh · US

Funding

Multidisciplinary Training in Critical Care Outcomes ResearchT32HL007820 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Timothy D Girard, Jeremy M Kahn · 1996 to 2026
$6.4M
Pittsburgh Career Development Program in Emergency Medicine ResearchK12HL109068 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CALLAWAY, CLIFTON W., YEALY, DONALD M · 2011 to 2015
$3.1M
Understanding Regional Critical Care Delivery in Acute Respiratory FailureK08HL122478 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WALLACE, DAVID JOHN · 2015 to 2018
$606k
Development of instrument--critical care organizationK23HL082650 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAHN, JEREMY M · 2006 to 2010
$576k
NHLBI NIH HHS K08 HL122478NHLBI NIH HHS K12 HL109068NHLBI NIH HHS K12HL109068NHLBI NIH HHS K23 HL082650NHLBI NIH HHS K23HL082650NHLBI NIH HHS T32 HL007820NHLBI NIH HHS T32HL007820
6 · The paper itself

Abstract

backgroundICUs are increasingly staffed with nurse practitioners/physician assistants (NPs/PAs), but it is unclear how NPs/PAs influence quality of care. We examined the association between NP/PA staffing and in-hospital mortality for patients in the ICU.

methodsWe used retrospective cohort data from the 2009 to 2010 APACHE (Acute Physiology and Chronic Health Evaluation) clinical information system and an ICU-level survey. We included patients aged ≥ 17 years admitted to one of 29 adult medical and mixed medical/surgical ICUs in 22 US hospitals. Because this survey could not assign NPs/PAs to individual patients, the primary exposure was admission to an ICU where NPs/PAs participated in patient care. The primary outcome was patient-level in-hospital mortality. We used multivariable relative risk regression to examine the effect of NPs/PAs on in-hospital mortality, accounting for differences in case mix, ICU characteristics, and clustering of patients within ICUs. We also examined this relationship in the following subgroups: patients on mechanical ventilation, patients with the highest quartile of Acute Physiology Score (> 55), and ICUs with low-intensity physician staffing and with physician trainees.

resultsTwenty-one ICUs (72.4%) reported NP/PA participation in direct patient care. Patients in ICUs with NPs/PAs had lower mean Acute Physiology Scores (42.4 vs 46.7, P < .001) and mechanical ventilation rates (38.8% vs 44.2%, P < .001) than ICUs without NPs/PAs. Unadjusted and risk-adjusted mortality was similar between groups (adjusted relative risk, 1.10; 95% CI, 0.92-1.31). This result was consistent in all examined subgroups.

conclusionsNPs/PAs appear to be a safe adjunct to the ICU team. The findings support NP/PA management of critically ill patients.

Indexed as

Intensive Care UnitsPersonnel Staffing and SchedulingAdolescentAdultAgedAged, 80 and overAPACHEBenchmarkingCritical CareCritical IllnessDatabases, FactualFemaleHealth Care SurveysHospital MortalityHumansMale

Identifiers

PMID25167081
PMCPMC4251618
OpenAlexW2122668224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.