Evidence map›Paper›PMID 25166906›Full record

SynthesisPLoS neglected tropical diseases2014

Toxocariasis in North America: a systematic review.

Rachel M Lee, Laura B Moore, Maria Elena Bottazzi, Peter J Hotez

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 4 pooled it
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Human toxocariasis.Clinical microbiology reviews · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. A Systematic Review of Toxocariasis: A Neglected But High-Prevalence Disease in Brazil.The American journal of tropical medicine and hygiene · 2016
    Pooled it
  5. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  6. Epidemiological study ofFrontiers in veterinary science · 2026
    Article
  7. Toxocariasis in 62-year-old man with eosinophilia.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Article
  8. Article
  9. Pathogens (Basel, Switzerland) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The epidemiology and control ofParasite epidemiology and control · 2022
    Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rachel M LeeBaylor College of Medicine, Houston, Texas, United States of America.
Laura B MooreJames A. Baker Institute of Public Policy, Rice University, Houston, Texas, United States of America.
Maria Elena BottazziDepartments of Medicine, Pediatrics, and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, Texas, United States of America.
Peter J HotezDepartments of Medicine, Pediatrics, and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, Texas, United States of America.
Baylor College of Medicine · USRice University · USSabin Vaccine Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxocariasis is an important neglected tropical disease that can manifest as visceral or ocular larva migrans, or covert toxocariasis. All three forms pose a public health problem and cause significant morbidity in areas of high prevalence. To determine the burden of toxocariasis in North America, we conducted a systematic review of the literature following PRISMA guidelines. We found 18 articles with original prevalence, incidence, or case data for toxocariasis. Prevalence estimates ranged from 0.6% in a Canadian Inuit community to 30.8% in Mexican children with asthma. Commonly cited risk factors included: African-American race, poverty, male sex, and pet ownership or environmental contamination by animal feces. Increased prevalence of Toxocara spp. infection was linked in a group of case control studies conducted in Mexico to several high risk groups including waste pickers, asthmatic children, and inpatient psychiatry patients. Further research is needed to determine the true current burden of toxocariasis in North America; however the prevalence estimates gathered in this review suggest that the burden of disease is significant.

Indexed as

ToxocariasisAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansMaleMiddle AgedNorth AmericaRisk FactorsYoung Adult

Identifiers

PMID25166906
PMCPMC4148222
OpenAlexW1990683804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.