ArticlePloS one2014
Characterization of the fecal microbiota of pigs before and after inoculation with "Brachyspira hampsonii".
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 57 citations in OpenAlex.
- Metabolomic signatures of colonic infection by Brachyspira hyodysenteriae.Veterinary research · 2026Article
- From predisposition to recovery: field evidence of interactions between the gut microbiota and Brachyspira hyodysenteriae infection.Veterinary research · 2026Article
- Exploring the potential for competitive exclusion of commensal probiotic candidates against the insidious swine pathogen Brachyspira hyodysenteriae.Animal microbiome · 2026Article
- Severity of Brachyspira hyodysenteriae colitis correlates to the changes observed in the microbiota composition and its associated functionality in the large intestine.Animal microbiome · 2025Article
- Comparative analysis of fecal microbiota between diarrhea and non-diarrhea piglets reveals biomarkers of gut microbiota associated with diarrhea.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Article
- Microbial Mechanistic Insight into the Role of Yeast-Derived Postbiotics in Improving Sow Reproductive Performance in Late Gestation and Lactation Sows.Animals : an open access journal from MDPI · 2024Article
- Rapid and accurate taxonomic classification of cpn60 amplicon sequence variants.ISME communications · 2023Article
- Characterization of the bacterial fecal microbiota composition of pigs preceding the clinical signs of swine dysentery.PloS one · 2023Article
- Metagenomic analysis fecal microbiota of dysentery-like diarrhoea in a pig farm using next-generation sequencing.Frontiers in veterinary science · 2023Article
- Characterization of Intestinal Microbiota in Lambs with Different Susceptibility toVeterinary sciences · 2022Article
- Lower abundance of Bacteroides and metabolic dysfunction are highly associated with the post-weaning diarrhea in piglets.Science China. Life sciences · 2022Article
- EnterotoxigenicFrontiers in immunology · 2022Review
- The dysbiosis of ovine foot microbiome during the development and treatment of contagious ovine digital dermatitis.Animal microbiome · 2021Article
- Relationships among Fecal, Air, Oral, and Tracheal Microbial Communities in Pigs in a Respiratory Infection Disease Model.Microorganisms · 2021Article
- Late weaning is associated with increased microbial diversity and Faecalibacterium prausnitzii abundance in the fecal microbiota of piglets.Animal microbiome · 2020Article
- Differently Pre-treated Rapeseed Meals AffectFrontiers in microbiology · 2020Article
- Article
- Longitudinal development of the gut microbiota in healthy and diarrheic piglets induced by age-related dietary changes.MicrobiologyOpen · 2019Article
- Intestinal microbiota mediates Enterotoxigenic Escherichia coli-induced diarrhea in piglets.BMC veterinary research · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Brachyspira hampsonii" causes disease indistinguishable from swine dysentery, and the structure of the intestinal microbiome likely plays a role in determining susceptibility of individual pigs to infection and development of clinical disease. The objectives of the current study were to determine if the pre-inoculation fecal microbiota differed between inoculated pigs that did (INOC MH) or did not (INOC non-MH) develop mucohaemorrhagic diarrhea following challenge with "B. hampsonii", and to quantify changes in the structure of the microbiome following development of clinical disease. Fecal microbiota profiles were generated based on amplification and sequencing of the cpn60 universal target sequence from 89 samples from 18 pigs collected at -8, -5, -3 and 0 days post-inoculation, and at termination. No significant differences in richness, diversity or taxonomic composition distinguished the pre-inoculation microbiomes of INOC MH and INOC non-MH pigs. However, the development of bloody diarrhea in inoculated pigs was associated with perturbation of the microbiota relative to INOC non-MH or sham-inoculated control pigs. Specifically, the fecal microbiota of INOC MH pigs was less dense (fewer total 16S rRNA copies per gram of feces), and had a lower Bacteroidetes:Firmicutes ratio. Further investigation of the potential long-term effects of Brachyspira disease on intestinal health and performance is warranted.
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