ArticleOptics letters2014
Photothermal laser speckle imaging.
Article in Optics letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Time-Resolved Laser Speckle Contrast Imaging (TR-LSCI) of Cerebral Blood Flow.IEEE transactions on medical imaging · 2025Article
- Lightweight denoising speckle contrast image GAN for real-time denoising of laser speckle imaging of blood flow.Biomedical optics express · 2025Article
- Signal amplification and quantification on lateral flow assays by laser excitation of plasmonic nanomaterials.Theranostics · 2020Review
- Visualization ofBiomedical optics express · 2019Article
- Momentum transfer Monte Carlo for the simulation of laser speckle imaging and its application in the skin.Biomedical optics express · 2017Article
- Laser speckle imaging based on photothermally driven convection.Journal of biomedical optics · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The analysis of speckle contrast in a time-integrated speckle pattern enables visualization of superficial blood flow in exposed vasculature, a method we call laser speckle imaging (LSI). With current methods, LSI does not enable visualization of subsurface or small vasculature, because of optical scattering by stationary structures. In this work we propose a new technique called photothermal LSI to improve the visualization of blood vessels. A 595 nm laser pulse was used to excite blood in both in vitro and in vivo samples. The high absorption coefficient of blood at this wavelength results in efficient conversion of optical energy to thermal energy, resulting in an increase in the local temperature and hence increased scatterer motion, and thus a transient decrease in speckle contrast. As a result, we found that photothermal LSI was able to visualize blood vessels that were hidden when imaged with a conventional LSI system.
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