ArticlePloS one2014
Identification of Lactobacillus from the saliva of adult patients with caries using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Highlighting Lactic Acid Bacteria in Beverages: Diversity, Fermentation, Challenges, and Future Perspectives.Foods (Basel, Switzerland) · 2025Review
- Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition.Frontiers in cellular and infection microbiology · 2023Article
- Determination and Identification of Antibiotic Drugs and Bacterial Strains in Biological Samples.Molecules (Basel, Switzerland) · 2020Review
- Identification, Classification and Screening for γ-Amino-butyric Acid Production in Lactic Acid Bacteria from Cambodian Fermented Foods.Biomolecules · 2019Article
- Article
- Relationship between tetracycline antibiotic susceptibility and genotype in oral cavityAntimicrobial resistance and infection control · 2019Article
- Functional eubacteria species along with trans-domain gut inhabitants favour dysgenic diversity in oxalate stone disease.Scientific reports · 2018Article
- Sensitivity of caries pathogens to antimicrobial peptides related to caries risk.Clinical oral investigations · 2018Article
- Article
- Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population.Advances in experimental medicine and biology · 2016Review
- Early and accurate detection of bacterial isolates from dental plaque in subjects with primary, mixed, and permanent dentition by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry technique.Journal of Indian Society of PeriodontologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS) has been presented as a superior method for the detection of microorganisms in body fluid samples (e.g., blood, saliva, pus, etc.) However, the performance of MALDI-TOF MS in routine identification of caries-related Lactobacillus isolates from saliva of adult patients with caries has not been determined. In the present study, we introduced a new MALDI-TOF MS system for identification of lactobacilli. Saliva samples were collected from 120 subjects with caries. Bacteria were isolated and cultured, and each isolate was identified by both 16S rRNA sequencing and MALDI-TOF MS. The identification results obtained by MALDI-TOF MS were concordant at the genus level with those of conventional 16S rRNA-based sequencing for 88.6% of lactobacilli (62/70) and 95.5% of non-lactobacilli (21/22). Up to 96 results could be obtained in parallel on a single MALDI target, suggesting that this is a reliable high-throughput approach for routine identification of lactobacilli. However, additional reference strains are necessary to increase the sensitivity and specificity of species-level identification.
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