ReviewTherapeutic advances in infectious disease2013
Blastocystis, an unrecognized parasite: an overview of pathogenesis and diagnosis.
Review in Therapeutic advances in infectious disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
119 citing papers in PubMed, 4 syntheses or guidelines pooled it, 201 citations in OpenAlex.
- Prevalence and subtype distribution of Blastocystis infections among community participants in Thailand: a systematic review and meta-analysis.Parasite (Paris, France) · 2025Pooled it
- Association between Blastocystis sp. infection and immunocompromised patients: a systematic review and meta-analysis.Environmental science and pollution research international · 2021Pooled it
- Comparative molecular prevalence and subtypes distribution of Blastocystis sp. a potentially zoonotic infection isolated from symptomatic and asymptomatic patients in Iran: A systematic review and meta-analysis.Acta parasitologica · 2021Pooled it
- Prevalence of Blastocystis sp. infection in several hosts in Brazil: a systematic review and meta-analysis.Parasites & vectors · 2020Pooled it
- Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the single-cell fecal parasitome in children with celiac disease autoimmunity: a randomized, double-blind placebo-controlled clinical trial.Parasites & vectors · 2023Trial
- MappingOne health (Amsterdam, Netherlands) · 2026Article
- Review
- Genetic diversity and zoonotic transmission potential ofParasite epidemiology and control · 2026Review
- Blastocystis infection enhances vitamins B and KBMC genomics · 2026Article
- Prevalence of Intestinal Protozoa Among Patients Living with HIV in the Peruvian Amazon.Tropical medicine and infectious disease · 2025Article
- From Bioinformatic Modeling to Clinical Observation: Potential Implications of Ribosomal RNA Folding inPathogens (Basel, Switzerland) · 2025Article
- Impact of Blastocystis carriage and colonization intensity on gut microbiota composition in a non-westernized rural population from Colombia.PLoS neglected tropical diseases · 2025Article
- Enhanced propionate and butyrate metabolism in cecal microbiota contributes to cold-stress adaptation in sheep.Microbiome · 2025Article
- The Role ofPathogens (Basel, Switzerland) · 2025Review
- Investigation ofAfrican health sciences · 2025Article
- Edible plants as significant sources ofFood and waterborne parasitology · 2025Review
- Molecular Identification and Genotyping ofArchives of Razi Institute · 2025Article
- One Health Disparities and Blastocystis infection among smallholder farmers in northeastern Madagascar.PLOS global public health · 2025Article
- Article
- Current status of intestinal parasitosis and microsporidiosis in industrialized countries: Results from a prospective study in France and Luxembourg.PLoS neglected tropical diseases · 2024Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blastocystis sp. is among the few enteric parasites with a prevalence that often exceeds 5% in the general population of industrialized countries and can reach 30-60% in developing countries. This parasite is frequently found in people who are immunocompromised (patients with human immunodeficiency virus/acquired immunodeficiency syndrome or cancer) and a higher risk of Blastocystis sp. infection has been found in people with close animal contact. Such prevalence in the human population and the zoonotic potential naturally raise questions about the impact of these parasites on public health and has increased interest in this area. Recent in vitro and in vivo studies have shed new light on the pathogenic power of this parasite, suggesting that Blastocystis sp. infection is associated with a variety of gastrointestinal disorders, may play a significant role in irritable bowel syndrome, and may be linked with cutaneous lesions (urticaria). Despite recent significant advances in the knowledge of the extensive genetic diversity of this species, the identification of extracellular proteases as virulence factors and the publication of one isolate genome, many aspects of the biology of Blastocystis sp. remain poorly investigated. In this review, we investigate several biological aspects of Blastocystis sp. (diversity and epidemiology, diagnosis tools and pathophysiology). These data pave the way for the following challenges concerning Blastocystis sp. research: deciphering key biological mechanisms and pathways of this parasite and clarification of its clinical impact in humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.