ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2014
How simple are 'simple renal cysts'?
Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Aspiration-sclerotherapy versus laparoscopic de-roofing in the treatment of renal cysts: which is better?BMC nephrology · 2020Pooled it
- Hyperuricemia and overexcretion of uric acid increase the risk of simple renal cysts in type 2 diabetes.Scientific reports · 2017Trial
- Factors Affecting the Presence of Renal Cortical Cysts in Kidney Donors.Urology research & practice · 2025Article
- Increased prevalence of kidney cysts in individuals carrying heterozygous COL4A3 or COL4A4 pathogenic variants.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- The prevalence and associated risk factors of detectable renal morphological abnormalities in acromegaly.Pituitary · 2024Article
- Multiple and large simple renal cysts are associated with glomerular filtration rate decline: a cross-sectional study of Chinese population.European journal of medical research · 2024Article
- Association Between Metabolic Syndrome and the Size of Renal Cysts: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Decline in measured glomerular filtration rate is associated with simple renal cyst in Chinese patients with type 2 diabetes.Journal of diabetes investigation · 2024Article
- CEUS Bosniak Classification-Time for Differentiation and Change in Renal Cyst Surveillance.Cancers · 2023Review
- Ultrasound-guided percutaneous intracystic deroofing is effective in the treatment of simple renal cysts.American journal of translational research · 2023Article
- Cystic Kidney Diseases That Require a Differential Diagnosis from Autosomal Dominant Polycystic Kidney Disease (ADPKD).Journal of clinical medicine · 2022Review
- Added value of coronal-T1W sequence to the lumbar MR imaging protocol for low back pain.Biomedica : revista del Instituto Nacional de Salud · 2022Article
- Development and external validation of a nomogram for predicting renal function based on preoperative data from in-hospital patients with simple renal cysts.The Journal of international medical research · 2022Article
- The presence of simple renal cysts is associated with an increased risk of albuminuria in young adults.The Korean journal of internal medicine · 2022Article
- Association of simple renal cysts with metabolic syndrome in adults.Frontiers in public health · 2022Article
- Practice Patterns for the Acceptance of Medically Complex Living Kidney Donors with Hematuria, Sickle Cell Trait, Smoking, Illegal Drug Use, or Urological Issues: A Multinational Survey.Avicenna journal of medicine · 2021Article
- Sustained volume decreases in simple renal cysts after sclerotherapy using NBCA with or without hydrodissection.Journal of interventional medicine · 2021Article
- Determinants of Kidney Function and Accuracy of Kidney Microcysts Detection in Patients Treated With Lithium Salts for Bipolar Disorder.Frontiers in pharmacology · 2021Article
- Long-term renal function in living kidney donors with simple renal cysts: A retrospective cohort study.Clinical transplantation · 2020Article
- Kidney Allograft Cyst Infection.Kidney international reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing use of medical imaging as an investigative tool is leading to the incidental and frequent finding of renal cysts in the general population. The presence of a solitary or multiple renal cysts has been generally considered benign in the absence of a family history of renal cystic disease or evidence of chronic kidney disease. Nonetheless, a number of recent studies have questioned this consensus by reported associations with the development of hypertension or malignant change. For these reasons, some clinicians consider the presence of renal cysts to be a contraindication to kidney donation. The situation is complicated by the different usage of the term 'simple' by some radiologists (to indicate non-complex lesions) or nephrologists (to indicate age-related non-hereditary lesions). We propose that the term 'simple' be replaced with the morphological description, Stage I renal cyst (Bosniak Classification). The presence of a Stage I renal cyst should not preclude kidney donation. However, occult renal disease should be excluded and appropriate donor assessment performed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.