Evidence map›Paper›PMID 25165087›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

Valley fever: finding new places for an old disease: Coccidioides immitis found in Washington State soil associated with recent human infection.

Anastasia P Litvintseva, Nicola Marsden-Haug, Steven Hurst, Heather Hill, Lalitha Gade, Elizabeth M Driebe, Cindy Ralston, Chandler Roe, Bridget M Barker, Marcia Goldoft and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 185 citations in OpenAlex.

  1. Urban soils along the Kern River and Los Gatos Creek are hotspots forApplied and environmental microbiology · 2026
    Article
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  5. Neonatal management and outcomes in the setting of disseminated coccidioidomycosis in pregnancy.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
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  7. Urban soils along the Kern River and Los Gatos Creek are hotspots forbioRxiv : the preprint server for biology · 2026
    Article
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  15. Coccidioidomycosis: a growing global concern.The Journal of antimicrobial chemotherapy · 2025
    Review
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  17. Article
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  20. Article

49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Anastasia P LitvintsevaMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Nicola Marsden-HaugWashington State Department of Health, Shoreline and Tumwater.
Steven HurstMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Heather HillBenton-Franklin Health District, Kennewick, Washington.
Lalitha GadeMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Elizabeth M DriebeTranslational Genomics Research Institute, Flagstaff, Arizona.
Cindy RalstonBenton-Franklin Health District, Kennewick, Washington.
Chandler RoeTranslational Genomics Research Institute, Flagstaff, Arizona.
Bridget M BarkerTranslational Genomics Research Institute, Flagstaff, Arizona.
Marcia GoldoftWashington State Department of Health, Shoreline and Tumwater.
Paul KeimTranslational Genomics Research Institute, Flagstaff, Arizona.
Ron WohrleWashington State Department of Health, Shoreline and Tumwater.
George R ThompsonCoccidioidomycosis Serology Laboratory, University of California, Davis.
David M EngelthalerTranslational Genomics Research Institute, Flagstaff, Arizona.
Mary E BrandtMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Tom ChillerMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · USTranslational Genomics Research Institute · USWashington State Department of Health · USSoutheast Health District · USUniversity of California, Davis · US

Funding

UC Davis Biostatistics CoreP01AI131568 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HARTIGAN-O'CONNOR, DENNIS J. · 2017 to 2021
$7.1M
Functional Analysis of Regions of Introgression Between Species of CoccidioidesK22AI104801 · NIAID · TRANSLATIONAL GENOMICS RESEARCH INST · PI BARKER, BRIDGET MARIE · 2014 to 2015
$271k
NIAID NIH HHS K22 AI104801NIAID NIH HHS P01 AI131568
6 · The paper itself

Abstract

We used real-time polymerase chain reaction and culture to demonstrate persistent colonization of soils by Coccidioides immitis, an agent of valley fever, in Washington State linked to recent human infections and located outside the endemic range. Whole-genome sequencing confirmed genetic identity between isolates from soil and one of the case-patients.

Indexed as

Endemic DiseasesSoil MicrobiologyCluster AnalysisCoccidioidesCoccidioidomycosisDNA, FungalGenome, FungalHumansMicrobiological TechniquesMolecular Sequence DataReal-Time Polymerase Chain ReactionSequence Analysis, DNASequence HomologyWashingtonDNA, FungalCoccidioidessoil detectionvalley feverWGS typing

Identifiers

PMID25165087
PMCPMC4296125
OpenAlexW2162577709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.