ArticleMagnetic resonance in medicine2015
Balanced UTE-SSFP for 19F MR imaging of complex spectra.
Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Rapid Fragment Screening byAngewandte Chemie (International ed. in English) · 2026Article
- Feasibility and optimization ofPhysics in medicine and biology · 2024Article
- In Vivo Fluorine Imaging Using 1.5 Tesla MRI for Depiction of Experimental Myocarditis in a Rodent Animal Model.International journal of biomedical imaging · 2023Article
- Review
- MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022Review
- In Vivo MRI Tracking of Tumor Vaccination and Antigen Presentation by Dendritic Cells.Molecular imaging and biology · 2022Review
- Nanotechnology as a Versatile Tool forPharmaceutics · 2022Review
- "Advances in cancer imaging and technology"-special collection -introductory Editorial.BJR open · 2022Article
- Detection and viability of murine NK cells in vivo in a lymphoma model using fluorine-19 MRI.NMR in biomedicine · 2021Article
- Optimizing trajectory ordering for fast radial ultra-short TE (UTE) acquisitions.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021Article
- Functional Imaging Using Fluorine (Methods in molecular biology (Clifton, N.J.) · 2021Article
- Fluorine (Methods in molecular biology (Clifton, N.J.) · 2021Article
- Perfluorocarbons-BasedInternational journal of nanomedicine · 2020Review
- An iterative sparse deconvolution method for simultaneous multicolorMagnetic resonance in medicine · 2020Article
- A systematic optimization ofNeuroImage · 2019Article
- Article
- Protein-Engineered Nanoscale Micelles for DynamicACS nano · 2019Article
- Improved compressed sensing reconstruction forMagma (New York, N.Y.) · 2019Article
- In vivoMagma (New York, N.Y.) · 2019Article
- Dual-ContrastCirculation. Cardiovascular imaging · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeA novel technique for highly sensitive detection of multiresonant fluorine imaging agents was designed and tested with the use of dual-frequency 19F/1H ultrashort echo times (UTE) sampled with a balanced steady-state free precession (SSFP) pulse sequence and three-dimensional (3D) radial readout.
methodsFeasibility of 3D radial balanced UTE-SSFP imaging was demonstrated for a phantom comprising liquid perfluorooctyl bromide (PFOB). Sensitivity of the pulse sequence was measured and compared with other sequences imaging the PFOB (CF2 )6 line group including UTE radial gradient-echo (GRE) at α = 30°, as well as Cartesian GRE, balanced SSFP, and fast spin-echo (FSE). The PFOB CF3 peak was also sampled with FSE.
resultsThe proposed balanced UTE-SSFP technique exhibited a relative detection sensitivity of 51 μmolPFOB(-1) min(-1/2) (α = 30°), at least twice that of other sequence types with either 3D radial (UTE GRE: 20 μmolPFOB(-1) min(-1/2) ) or Cartesian k-space filling (GRE: 12 μmolPFOB(-1) min(-1/2) ; FSE: 16 μmolPFOB(-1) min(-1/2) ; balanced SSFP: 23 μmolPFOB(-1) min(-1/2) ). In vivo imaging of angiogenesis-targeted PFOB nanoparticles was demonstrated in a rabbit model of cancer on a clinical 3 Tesla scanner.
conclusionA new dual 19F/1H balanced UTE-SSFP sequence manifests high SNR, with detection sensitivity more than two-fold better than traditional techniques, and alleviates imaging problems caused by dephasing in complex spectra.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.