Evidence map›Paper›PMID 25163410›Full record

ArticleHepatology (Baltimore, Md.)2015

Endoplasmic reticulum heat shock protein gp96/grp94 is a pro-oncogenic chaperone, not a tumor suppressor.

Saleh Rachidi, Shaoli Sun, Zihai Li

Abstract readLetterComment
In one paragraph

Article in Hepatology (Baltimore, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.Current topics in medicinal chemistry · 2016
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Saleh RachidiDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC.
Shaoli Sun
Zihai Li

Funding

Project 3: Structural Basis for grp94 Drug Development and Chaperone FunctionP01CA186866 · NCI · OHIO STATE UNIVERSITY · PI LI, ZIHAI · 2015 to 2019
$6.7M
Roles and Mechanisms of gp96 in Chaperoning Innate ImmunityR01AI070603 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LI, ZIHAI · 2007 to 2016
$3.8M
Thrombocytes in Cancer ImmunityR01CA188419 · NCI · OHIO STATE UNIVERSITY · PI LI, ZIHAI · 2015 to 2019
$1.9M
NCI NIH HHS P01 CA186866NCI NIH HHS R01 CA188419NIAID NIH HHS R01 AI070603
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCarcinogenesisHumansLiver Neoplasms, ExperimentalMembrane GlycoproteinsNeoplastic Stem CellsMembrane Glycoproteins

Identifiers

PMID25163410
PMCPMC4939405

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.