ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2015
Suppression of subthalamic nucleus activity by micromagnetic stimulation.
Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 35 citations in OpenAlex.
- Micro-Coil Neuromodulation at Single-Cell and Circuit Levels for Inhibiting Natural Neuroactivity, Neutralizing Electric Neural Excitation, and Suppressing Seizures.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Microfabrication Technologies for Nanoinvasive and High-Resolution Magnetic Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- System-level biological effects of extremely low-frequency electromagnetic fields: anFrontiers in neuroscience · 2023Review
- Thermal effects on neurons during stimulation of the brain.Journal of neural engineering · 2022Article
- Micro-magnetic stimulation of primary visual cortex induces focal and sustained activation of secondary visual cortex.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022Article
- Selective Activation of Cortical Columns Using Multichannel Magnetic Stimulation With a Bent Flat Microwire Array.IEEE transactions on bio-medical engineering · 2021Article
- MEMS inductor fabrication and emerging applications in power electronics and neurotechnologies.Microsystems & nanoengineering · 2021Review
- Micro-Coil Design Influences the Spatial Extent of Responses to Intracortical Magnetic Stimulation.IEEE transactions on bio-medical engineering · 2019Article
- Planar coil-based contact-mode magnetic stimulation: synaptic responses in hippocampal slices and thermal considerations.Scientific reports · 2018Article
- Enhanced Control of Cortical Pyramidal Neurons With Micromagnetic Stimulation.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2017Article
- Modeling Intracochlear Magnetic Stimulation: A Finite-Element Analysis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2017Article
- Implantable microcoils for intracortical magnetic stimulation.Science advances · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Magnetic stimulation delivered via 0.5-mm diameter coils was recently shown to activate retinal neurons; the small coil size raises the possibility that micromagnetic stimulation ( μMS) could underlie a new generation of implanted neural prosthetics. Such an approach has several inherent advantages over conventional electric stimulation, including the potential for selective activation of neuronal targets as well as less susceptibility to inflammatory responses. The viability of μMS for some applications, e.g., deep brain stimulation (DBS), may require suppression (rather than creation) of neuronal activity, however, and therefore we explore here whether (μMS) could, in fact, suppress activity. While single pulses elicited weak and inconsistent spiking in neurons of the mouse subthalamic nucleus (in vitro), repetitive stimulation effectively suppressed activity in ∼ 70% of targeted neurons. This is the same percentage suppressed by conventional electric stimulation; with both modalities, suppression occurred only after an initial increase in spiking. The latency to the onset of suppression was inversely correlated to the energy of the stimulus waveform: larger amplitudes and lower frequencies had the fastest onset of suppression. These findings continue to support the viability of μMS as a next-generation implantable neural prosthetic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.