ArticleJournal of women's health (2002)2014
The impact of vulvar lichen sclerosus on sexual dysfunction.
Article in Journal of women's health (2002), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 95 citations in OpenAlex.
- Randomized clinical trial with fractional COBMC research notes · 2023Trial
- The Efficacy of an Optimized, Low-Intensity Photodynamic Therapy Protocol with 10% 5-ALA Nanoemulsion in Refractory Vulvar Lichen Sclerosus: Impact on Quality of Life and Sexual Function.Journal of clinical medicine · 2026Article
- Exploring Genital Lichen Sclerosus: Navigating from Pathophysiology to Precise Diagnostic Approaches.Biomedicines · 2025Review
- Vulval lichen sclerosus in UK general practice: a cross-sectional survey of patient experience.BMJ open · 2025Article
- Patient satisfaction and sexual issues in vulvar lichen sclerosus treatment: a monocentric certified dysplasia unit survey analysis.Archives of gynecology and obstetrics · 2024Article
- The impact of genital lichen sclerosus in men and women on quality of life: a prospective cohort study.International journal of women's dermatology · 2024Article
- Vulvodynia, Genital Eczema and Lichen Sclerosus: What are the Successful Treatments from a Patient's Perspective?International journal of women's health · 2024Article
- Article
- Lichen Sclerosus: A Current Landscape of Autoimmune and Genetic Interplay.Diagnostics (Basel, Switzerland) · 2022Review
- Living with vulval lichen sclerosus: a qualitative interview study.The British journal of dermatology · 2022Article
- Genital Self-Image, Sexual Function, and Quality of Life Among Individuals with Vulvar and Non-Vulvar Inflammatory Dermatoses.Archives of sexual behavior · 2022Article
- Quality of life impact and treatment response in vulval disease: Comparison of 3 common conditions using the Vulval Quality of Life Index.The Australasian journal of dermatology · 2022Article
- Why do some patients with vulval lichen sclerosus on long-term topical corticosteroid treatment experience ongoing poor quality of life?The Australasian journal of dermatology · 2022Article
- Fractional COLasers in surgery and medicine · 2022Article
- Differentially Regulated miRNAs and Their Related Molecular Pathways in Lichen Sclerosus.Cells · 2021Article
- Vulvar lichen sclerosus in women of reproductive age.Proceedings (Baylor University. Medical Center) · 2021Article
- Living with vulval lichen sclerosus: Unheard stories and silenced voices.Case reports in women's health · 2021Article
- Decreased Sexual Desire among Middle-Aged and Old Women in China and Factors Influencing It: A Questionnaire-Based Study.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Vulvar Pruritus: A Review of Clinical Associations, Pathophysiology and Therapeutic Management.Frontiers in medicine · 2021Review
- Vulvar leukoplakia: therapeutic options.Przeglad menopauzalny = Menopause review · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLichen sclerosus (LS) is a chronic inflammatory condition that is known to arise on the vulva. Many women with LS report vulvar pain, often affecting a patient's quality of life. In this study, the sexual function of LS patients, with and without pain, was compared to control populations. MATERIALS AND
methodsA case-control study to examine the relationship between LS and sexual dysfunction was conducted. A total of 335 women presenting to the gynecology clinic were included in the study: 197 women with biopsy confirmed LS were compared to two control groups (95 asymptomatic women were "healthy" controls and 43 women had vulvovaginal candidiasis) on self-reported current health complaints, medical and surgical history and current symptoms such as pain and itching, type and frequency of sexual activity, and satisfaction with sexual activity.
resultsWomen with LS reported less frequent sexual activity than healthy controls (p=0.007) and Candida controls (p=0.04). Currently sexually active women with LS were significantly less likely to report vaginal intercourse (71.6%) than healthy controls (89.0%, p=0.003) or Candida controls (100%, p=0.0003), even though similar proportions of all three groups reported that vaginal intercourse was important. Satisfaction towards the quality of current sexual activity was significantly lower among women with LS compared with both the healthy and Candida control groups. 23.7% of women with LS reported that sexual activity was rarely or never satisfactory as compared with 0% of healthy controls (p<0.0001) and 6.5% of Candida controls (p=0.03).
conclusionWomen with LS have less frequent sexual activity and less satisfying sexual activity when compared with controls.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.