Evidence map›Paper›PMID 25162399›Full record

ArticlePloS one2014

Ubiquity and diversity of human-associated Demodex mites.

Megan S Thoemmes, Daniel J Fergus, Julie Urban, Michelle Trautwein, Robert R Dunn

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 85 citations in OpenAlex.

  1. First Detection of Human- and Dog-AssociatedPathogens (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Diagnostics (Basel, Switzerland) · 2025
    Article
  4. Epidemiological survey of two morphotypes ofParasite epidemiology and control · 2024
    Article
  5. The Prevalence ofLife (Basel, Switzerland) · 2024
    Article
  6. A new species ofInternational journal for parasitology. Parasites and wildlife · 2024
    Article
  7. Review
  8. Article
  9. In Vivo View of a Reclining Demodex Mite in a Milia Cyst.Diagnostics (Basel, Switzerland) · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Dermatology reports · 2022
    Article
  14. Human follicular mites: Ectoparasites becoming symbionts.Molecular biology and evolution · 2022
    Article
  15. Treatment of ocularAmerican journal of ophthalmology case reports · 2022
    Article
  16. NovelPostepy dermatologii i alergologii · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Detection ofJournal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Megan S ThoemmesDepartment of Biological Sciences and W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, North Carolina, United States of America.
Daniel J FergusDepartment of Biological Sciences and W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, North Carolina, United States of America; North Carolina Museum of Natural Sciences, Raleigh, North Carolina, United States of America.
Julie UrbanNorth Carolina Museum of Natural Sciences, Raleigh, North Carolina, United States of America.
Michelle TrautweinCalifornia Academy of Sciences, San Francisco, California, United States of America; Department of Entomology, North Carolina State University, Raleigh, North Carolina, United States of America.
Robert R DunnDepartment of Biological Sciences and W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, North Carolina, United States of America.
North Carolina State University · USNorth Carolina Museum of Natural Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Demodex mites are a group of hair follicle and sebaceous gland-dwelling species. The species of these mites found on humans are arguably the animals with which we have the most intimate interactions. Yet, their prevalence and diversity have been poorly explored. Here we use a new molecular method to assess the occurrence of Demodex mites on humans. In addition, we use the 18S rRNA gene (18S rDNA) to assess the genetic diversity and evolutionary history of Demodex lineages. Within our samples, 100% of people over 18 years of age appear to host at least one Demodex species, suggesting that Demodex mites may be universal associates of adult humans. A phylogenetic analysis of 18S rDNA reveals intraspecific structure within one of the two named human-associated Demodex species, D. brevis. The D. brevis clade is geographically structured, suggesting that new lineages are likely to be discovered as humans from additional geographic regions are sampled.

Indexed as

Genes, rRNAPhylogenyAdolescentAdultAnimalsFemaleGenetic VariationHair FollicleHumansMaleMiddle AgedMite InfestationsMitesPrevalenceRNA, Ribosomal, 16SRNA, Ribosomal, 18SRNA, Ribosomal, 16SRNA, Ribosomal, 18S

Identifiers

PMID25162399
PMCPMC4146604
OpenAlexW2040687821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.