Evidence map›Paper›PMID 25162022›Full record

ArticleBioMed research international2014

The properties of binding sites of miR-619-5p, miR-5095, miR-5096, and miR-5585-3p in the mRNAs of human genes.

Anatoly Ivashchenko, Olga Berillo, Anna Pyrkova, Raigul Niyazova, Shara Atambayeva

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Circulating hsa-miR-5096 predictsFrontiers in oncology · 2023
    Article
  2. Article
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  4. Prediction of miRNA interaction with mRNA of stroke candidate genes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  5. Frontiers in genetics · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anatoly IvashchenkoNational Nanotechnology Laboratory, Al-Farabi Kazakh National University, Almaty 050038, Kazakhstan.
Olga BerilloNational Nanotechnology Laboratory, Al-Farabi Kazakh National University, Almaty 050038, Kazakhstan.
Anna PyrkovaNational Nanotechnology Laboratory, Al-Farabi Kazakh National University, Almaty 050038, Kazakhstan.
Raigul NiyazovaNational Nanotechnology Laboratory, Al-Farabi Kazakh National University, Almaty 050038, Kazakhstan.
Shara AtambayevaNational Nanotechnology Laboratory, Al-Farabi Kazakh National University, Almaty 050038, Kazakhstan.
Al-Farabi Kazakh National University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The binding of 2,578 human miRNAs with the mRNAs of 12,175 human genes was studied. It was established that miR-619-5p, miR-5095, miR-5096, and miR-5585-3p bind with high affinity to the mRNAs of the 1215, 832, 725, and 655 genes, respectively. These unique miRNAs have binding sites in the coding sequences and untranslated regions of mRNAs. The mRNAs of many genes have multiple miR-619-5p, miR-5095, miR-5096, and miR-5585-3p binding sites. Groups of mRNAs in which the ordering of the miR-619-5p, miR-5095, miR-5096, and miR-5585-3p binding sites differ were established. The possible functional and evolutional properties of unique miRNAs are discussed.

Indexed as

Binding SitesGene Expression RegulationHumansMicroRNAsRNA, MessengerMicroRNAsMIRN-5095 microRNA, humanMIRN-5096 microRNA, humanMIRN-5585 microRNA, humanMIRN-619 microRNA, humanRNA, Messenger

Identifiers

PMID25162022
PMCPMC4137733
OpenAlexW2055093111

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.