Evidence map›Paper›PMID 25161903›Full record

ArticleInternational journal for parasitology. Parasites and wildlife2014

Proteomic profile of Ortleppascaris sp.: A helminth parasite of Rhinella marina in the Amazonian region.

Jefferson Pereira E Silva, Adriano Penha Furtado, Jeannie Nascimento Dos Santos

Open access · goldAbstract read
In one paragraph

Article in International journal for parasitology. Parasites and wildlife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jefferson Pereira E SilvaLaboratory of Cell Biology and Helminthology (Laboratório de Biologia Celular e Helmintologia) "Profa. Dra. Reinalda Marisa Lanfredi", Biological Sciences Institute (Instituto de Ciências Biológicas), Federal University of Pará (Universidade Federal do Pará), Belém, Pará, Brazil.
Adriano Penha FurtadoLaboratory of Cell Biology and Helminthology (Laboratório de Biologia Celular e Helmintologia) "Profa. Dra. Reinalda Marisa Lanfredi", Biological Sciences Institute (Instituto de Ciências Biológicas), Federal University of Pará (Universidade Federal do Pará), Belém, Pará, Brazil.
Jeannie Nascimento Dos SantosLaboratory of Cell Biology and Helminthology (Laboratório de Biologia Celular e Helmintologia) "Profa. Dra. Reinalda Marisa Lanfredi", Biological Sciences Institute (Instituto de Ciências Biológicas), Federal University of Pará (Universidade Federal do Pará), Belém, Pará, Brazil.
Universidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ortleppascaris sp. is a helminth that, in its larval stage, infects the liver parenchyma of the amphibian Rhinella marina, resulting in severe physiological and pathological changes. This study used a proteomic approach to determine the overall profile of proteins expressed in a somatic extract from the nematodes to investigate the relationship between the parasite and its host. A total of 60 abundant proteins were selected from the two-dimensional electrophoresis, identified by peptide mass fingerprinting, and grouped based on their Gene Ontology by the biological processes in which they are potentially involved. Important helminthic derivatives, such as the immunoreactive As37 antigen, guanylyl cyclases, proteolytic enzymes, and other proteins conserved among different parasites, were identified through homology. This study represents a new approach to helminth-related proteomic studies using an amphibian animal model. Furthermore, this study identified protein markers that are important to the host-parasite relationship and the viability, development, infectivity, and virulence of helminths.

Indexed as

Amazonian amphibianMass spectrometryNematodeOrtleppascarisSomatic proteome

Identifiers

PMID25161903
PMCPMC4142265
OpenAlexW2066928814

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.