Evidence map›Paper›PMID 25161823›Full record

Trial reportBrain and behavior2014

Biofeedback-based training for stress management in daily hassles: an intervention study.

Yuka Kotozaki, Hikaru Takeuchi, Atsushi Sekiguchi, Yuki Yamamoto, Takamitsu Shinada, Tsuyoshi Araki, Kei Takahashi, Yasuyuki Taki, Takeshi Ogino, Masashi Kiguchi and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yuka KotozakiSmart Ageing International Research Center, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Hikaru TakeuchiDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Atsushi SekiguchiDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan ; Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University Sendai, Japan.
Yuki YamamotoDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Takamitsu ShinadaDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Tsuyoshi ArakiSmart Ageing International Research Center, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Kei TakahashiDepartment of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Yasuyuki TakiDivision of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan ; Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University Sendai, Japan ; Department of Radiology and Nuclear Medicine, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Takeshi OginoHitachi Ltd. Tokyo, Japan.
Masashi KiguchiCentral Research Laboratory, Hitachi, Ltd. Saitama, Japan.
Ryuta KawashimaSmart Ageing International Research Center, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan ; Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan ; Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, Tohoku University Sendai, Japan.
Tohoku University · JPHitachi (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe day-to-day causes of stress are called daily hassles. Daily hassles are correlated with ill health. Biofeedback (BF) is one of the tools used for acquiring stress-coping skills. However, the anatomical correlates of the effects of BF with long training periods remain unclear. In this study, we aimed to investigate this.

methodsPARTICIPANTS WERE ASSIGNED RANDOMLY TO TWO GROUPS: the intervention group and the control group. Participants in the intervention group performed a biofeedback training (BFT) task (a combination task for heart rate and cerebral blood flow control) every day, for about 5 min once a day. The study outcomes included MRI, psychological tests (e.g., Positive and Negative Affect Schedule, Center for Epidemiologic Studies Depression Scale, and Brief Job Stress Questionnaire), and a stress marker (salivary cortisol levels) before (day 0) and after (day 28) the intervention.

resultsWe observed significant improvements in the psychological test scores and salivary cortisol levels in the intervention group compared to the control group. Furthermore, voxel-based morphometric analysis revealed that compared to the control group, the intervention group had significantly increased regional gray matter (GM) volume in the right lateral orbitofrontal cortex, which is an anatomical cluster that includes mainly the left hippocampus, and the left subgenual anterior cingulate cortex. The GM regions are associated with the stress response, and, in general, these regions seem to be the most sensitive to the detrimental effects of stress.

conclusionsOur findings suggest that our BFT is effective against the GM structures vulnerable to stress.

Indexed as

Adaptation, PsychologicalAdultAffectBiofeedback, PsychologyCerebrovascular CirculationDouble-Blind MethodFemaleHeart RateHumansMaleMiddle AgedStress, PsychologicalTreatment OutcomeYoung AdultBiofeedback trainingdaily hassleshippocampusorbitofrontal cortexsubgenual anterior cingulate cortex

Identifiers

PMID25161823
PMCPMC4128038
OpenAlexW2064358489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.