Evidence map›Paper›PMID 25161068›Full record

ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2014

Comparative efficacy of the generalized anxiety disorder 7-item scale and the Edinburgh Postnatal Depression Scale as screening tools for generalized anxiety disorder in pregnancy and the postpartum period.

William Simpson, Melanie Glazer, Natalie Michalski, Meir Steiner, Benicio N Frey

Registry-linked trialOpen access · bronzeAbstract readComparative StudyValidation Study
In one paragraph

Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04153864 (Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment), which is not on this map. Cited by 102 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04153864 nacompletednot on this mapstarted 2020, after this paper: background citation

Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT): A Pragmatic, Non-inferiority Trial for Perinatal Depression and Anxiety

TypeinterventionalSponsorMount Sinai Hospital, CanadaRan2020 to 2025Enrolled1,230ConditionsPerinatal DepressionArmsBrief Behavioral Activation Treatment
3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 2 syntheses or guidelines pooled it, 212 citations in OpenAlex.

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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

William SimpsonStudent, MiNDS Neuroscience Program, McMaster University, Hamilton, Ontario.
Melanie GlazerStudent, Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, Ontario.
Natalie MichalskiStudent, Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, Ontario.
Meir SteinerProfessor Emeritus, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario; Psychiatrist, Women's Health Concerns Clinic, St Joseph's Healthcare, Hamilton, Ontario.
Benicio N FreyAssociate Professor, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario; Director, Women's Health Concerns Clinic, St Joseph's Healthcare, Hamilton, Ontario; Academic Head, Mood Disorders Program, St Joseph's Healthcare, Hamilton, Ontario.
McMaster University · CASt. Joseph’s Healthcare Hamilton · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAbout 24.1% of pregnant women suffer from at least 1 anxiety disorder, 8.5% of whom suffer specifically from generalized anxiety disorder (GAD). GAD is often associated with major depressive disorder (MDD). During the perinatal period, the presence of physical and somatic symptoms often makes differentiation between depression and anxiety more challenging. To date, no screening tools have been developed to detect GAD in the perinatal population. We investigated the psychometric properties of the GAD 7-item Scale (GAD-7) as a screening tool for GAD in pregnant and postpartum women.

methodsTwo hundred and forty perinatal women (n = 155 pregnant and n = 85 postpartum) referred for psychiatric consultation were enrolled. On the day of initial assessment, all women completed the GAD-7 and the Edinburgh Postnatal Depression Scale (EPDS). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-based diagnoses were made by experienced psychiatrists. Scores from the GAD-7 and EPDS were compared with the clinical diagnoses to evaluate the psychometric properties of the GAD-7 and EPDS when used as a screening tool for GAD.

resultsThe GAD-7 yielded a sensitivity of 61.3% and specificity of 72.7% at an optimal cut-off score of 13. Compared with the EPDS and the EPDS-3A subscale, the GAD-7 displayed greater accuracy and specificity over a greater range of cut-off scores and more accurately identified GAD in patients with comorbid MDD.

conclusionOur findings suggest that the GAD-7 represents a clinically useful scale for the detection of GAD in perinatal women.

Indexed as

AdolescentAdultAnxiety DisordersComorbidityDepression, PostpartumFemaleHumansMajor Depressive DisorderMass ScreeningMiddle AgedOntarioPregnancyPregnancy ComplicationsPsychometricsReproducibility of ResultsYoung Adult

Identifiers

PMID25161068
PMCPMC4143300
OpenAlexW27397971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.