Evidence map›Paper›PMID 25160635›Full record

ReviewMolecular oncology2014

Molecular pathology - the value of an integrative approach.

Manuel Salto-Tellez, Jacqueline A James, Peter W Hamilton

Abstract readReview
In one paragraph

Review in Molecular oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. The ins and outs of molecular pathology reporting.Virchows Archiv : an international journal of pathology · 2017
    Review
  10. Article
  11. Review
  12. The Role of ATRX in Glioma Biology.Frontiers in oncology · 2017
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manuel Salto-TellezNorthern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology, Queen's University, Belfast, Northern Ireland, UK; Tissue Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK. Electronic address: m.salto-tellez@qub.ac.uk.
Jacqueline A JamesNorthern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology, Queen's University, Belfast, Northern Ireland, UK; Tissue Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Peter W HamiltonNorthern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology, Queen's University, Belfast, Northern Ireland, UK.

Funding

Cancer Research UK
6 · The paper itself

Abstract

Molecular Pathology (MP) is at the heart of modern diagnostics and translational research, but the controversy on how MP is best developed has not abated. The lack of a proper model or trained pathologists to support the diagnostic and research missions makes MP a rare commodity overall. Here we analyse the scientific and technology areas, in research and diagnostics, which are encompassed by MP of solid tumours; we highlight the broad overlap of technologies and analytical capabilities in tissue research and diagnostics; and we describe an integrated model that rationalizes technical know-how and pathology talent for both. The model is based on a single, accredited laboratory providing a single standard of high-quality for biomarker discovery, biomarker validation and molecular diagnostics.

Indexed as

AnimalsBiomarkers, TumorComputational BiologyHumansNeoplasmsPathology, MolecularTissue BanksTranslational Research, BiomedicalBiomarkers, TumorMolecular diagnosticsMolecular pathologyTranslational research

Identifiers

PMID25160635
PMCPMC5528577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.