Evidence map›Paper›PMID 25159830›Full record

ArticleJournal of biological dynamics2015

Sticky surface: sphere-sphere adhesion dynamics.

Sarthok Sircar, John G Younger, David M Bortz

Abstract read
In one paragraph

Article in Journal of biological dynamics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Ligand-mediated adhesive mechanics of two static, deformed spheres.The European physical journal. E, Soft matter · 2016
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarthok Sircara School of Mathematical Sciences , University of Adelaide , Adelaide , SA 5000 , Australia.
John G Younger
David M Bortz

Funding

Biomechanics of Blood Stream InfectionsR01GM081702 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOLOMON, MICHAEL J · 2009 to 2017
$3.2M
NIGMS NIH HHS 1R01GM081702-01A2NIGMS NIH HHS R01 GM081702
6 · The paper itself

Abstract

We present a multi-scale model to study the attachment of spherical particles with a rigid core, coated with binding ligands and suspended in the surrounding, quiescent fluid medium. This class of fluid-immersed adhesion is widespread in many natural and engineering settings, particularly in microbial surface adhesion. Our theory highlights how the micro-scale binding kinetics of these ligands, as well as the attractive/repulsive surface potential in an ionic medium affects the eventual macro-scale size distribution of the particle aggregates (flocs). The bridge between the micro-macro model is made via an aggregation kernel. Results suggest that the presence of elastic ligands on the particle surface lead to the formation of larger floc aggregates via efficient inter-floc collisions (i.e. non-zero sticking probability, g). Strong electrolytic composition of the surrounding fluid favours large floc formation as well. The kernel for the Brownian diffusion for hard spheres is recovered in the limit of perfect binding effectiveness (g→1) and in a neutral solution with no dissolved salts.

Indexed as

MicrospheresModels, TheoreticalAdhesivenessAlgorithmsComputer SimulationDiffusionKineticsLigandsNumerical Analysis, Computer-AssistedProbabilityLigandsaggregationbinding ligandsSmoluchowski coagulation equationssticking probability

Identifiers

PMID25159830
PMCPMC4344442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.