Evidence map›Paper›PMID 25158949›Full record

Trial reportJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2014

Demineralization adjacent to orthodontic brackets after application of conventional and self-etching primer systems.

D Visel, Theresa Jäcker, T Jäcker, P-G Jost-Brinkmann, T-M Präger

Erratum issued Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05738356 (Comparison of Three Orthodontic Bonding Systems in White Spot Lesion Development), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05738356 nacompletednot on this mapstarted 2021, after this paper: background citation

Comparison of Three Orthodontic Bonding Systems in White Spot Lesion Development: A Randomized Clinical Trial

TypeinterventionalSponsorJordan University of Science and TechnologyRan2021 to 2023Enrolled75ConditionsWhite Spot LesionArmsAdhesive bonding systems
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Use of bioluminescence measurements for detection of artificial demineralization adjacent to orthodontic brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023
    Trial
  4. Trial
  5. Review
  6. Article
  7. A comparison of different sealants preventing demineralization around brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

D ViselDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité - Center for Dentistry, Oral Medicine and Maxillofacial Surgery, Assmannshauser Str. 4-6, 14197, Berlin, Germany, dominikvisel@googlemail.com.
Theresa Jäcker
T Jäcker
P-G Jost-Brinkmann
T-M Präger
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe goal of this work was to compare the demineralization of enamel associated with two different self-etching primers and traditional acid etching. MATERIALS AND

methodsA total of 15 volunteers (23-32 years, 8 male and 7 female) were provided with a removable archwire/resin appliance to be worn 20 h/day for 28 days. The device was attached to the mandibular posterior teeth and included samples of human enamel (from extracted third molars) located in both posterior vestibules. Both sides featured the same distribution of samples, including one untreated control sample (group A) and three samples with brackets (Victory™ APC II) bonded to their surface after conditioning with a self-etching non-fluoride primer (iBond™ Gluma® Inside; group B), a self-etching fluoride-releasing primer (Transbond™ Plus; group C), or traditional acid-etching with 35% phosphoric acid and Transbond™ XT (group D). Mineral loss was assessed extraorally under standardized conditions using quantitative light-induced fluorescence (QLF) with a specialized camera system (Inspektor Pro). Results were expressed as relative fluorescence loss (ΔF in %). A baseline measurement (T0) was taken before the appliance was first inserted but with the brackets already bonded. Fluorescence loss was analyzed after 3 (T1), 7 (T2), 14 (T3), and 28 days (T4) and compared to the baseline loss (T0) for each of the four study groups (A to D). Kruskal-Wallis and Mann-Whitney U tests were used to compare the results for statistical significance.

resultsThe lowest percentages of fluorescence loss both at baseline and during the follow-up assessments was found in group C. While all three experimental groups (B, C, D) presented total decreases in fluorescence loss after 28 days, indicating remineralization, the decrease in group C was the largest. The Kruskal-Wallis test yielded no significant differences between the three groups other than a significantly lower percentage of fluorescence loss in group C than in group D during the last assessment (T4). The untreated samples of control enamel (group A) revealed increasing percentages of fluorescence loss over the entire study period.

conclusionUse of the self-etching primers (groups B and C) was not associated with patterns of enamel demineralization different from those noted after traditional etching with phosphoric acid (group D). The only significant difference we observed was between the self-etching fluoride-releasing primer (group C) and traditional etching (group D) at the final assessment (T4). Thus, the fluoride-releasing system Transbond™ Plus was advantageous.

Indexed as

AdultBisphenol A-Glycidyl MethacrylateDental EnamelDental EtchingFemaleHumansMaleOrthodontic BracketsResin CementsTooth DemineralizationTreatment OutcomeYoung AdultBisphenol A-Glycidyl MethacrylateiBondResin CementsTransbond

Identifiers

PMID25158949
OpenAlexW147272034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.