Trial reportJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2014
Demineralization adjacent to orthodontic brackets after application of conventional and self-etching primer systems.
Trial report in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05738356 (Comparison of Three Orthodontic Bonding Systems in White Spot Lesion Development), which is not on this map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Three Orthodontic Bonding Systems in White Spot Lesion Development: A Randomized Clinical Trial
Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- In-vitro and in-vivo comparative studies of treatment effects on enamel demineralization during orthodontic therapy: implications for clinical early-intervention strategy.Clinical oral investigations · 2024Trial
- Comparison of three orthodontic bonding systems in white spot lesion development: a randomized clinical trial.The Angle orthodontist · 2023Trial
- Use of bioluminescence measurements for detection of artificial demineralization adjacent to orthodontic brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023Trial
- Impact of self-assembling peptides in remineralisation of artificial early enamel lesions adjacent to orthodontic brackets.Scientific reports · 2020Trial
- Surface Integrity of Widely Used Resin-Modified Glass Ionomers: New Findings Amid Limited Scientific Literature.Journal of clinical and experimental dentistry · 2026Review
- Assessment of enamel surface roughness and hardness with metal and ceramic orthodontic brackets using different etching and adhesive systems: AnThe Saudi dental journal · 2023Article
- A comparison of different sealants preventing demineralization around brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2018Article
Corrections and comments
- Erratum issuedErratum to: Evaluation of demineralization adjacent to orthodontic brackets after application of conventional and self-etching primer.2015 · Jäcker, T [corrected to Jäcker, Theresa]
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe goal of this work was to compare the demineralization of enamel associated with two different self-etching primers and traditional acid etching. MATERIALS AND
methodsA total of 15 volunteers (23-32 years, 8 male and 7 female) were provided with a removable archwire/resin appliance to be worn 20 h/day for 28 days. The device was attached to the mandibular posterior teeth and included samples of human enamel (from extracted third molars) located in both posterior vestibules. Both sides featured the same distribution of samples, including one untreated control sample (group A) and three samples with brackets (Victory™ APC II) bonded to their surface after conditioning with a self-etching non-fluoride primer (iBond™ Gluma® Inside; group B), a self-etching fluoride-releasing primer (Transbond™ Plus; group C), or traditional acid-etching with 35% phosphoric acid and Transbond™ XT (group D). Mineral loss was assessed extraorally under standardized conditions using quantitative light-induced fluorescence (QLF) with a specialized camera system (Inspektor Pro). Results were expressed as relative fluorescence loss (ΔF in %). A baseline measurement (T0) was taken before the appliance was first inserted but with the brackets already bonded. Fluorescence loss was analyzed after 3 (T1), 7 (T2), 14 (T3), and 28 days (T4) and compared to the baseline loss (T0) for each of the four study groups (A to D). Kruskal-Wallis and Mann-Whitney U tests were used to compare the results for statistical significance.
resultsThe lowest percentages of fluorescence loss both at baseline and during the follow-up assessments was found in group C. While all three experimental groups (B, C, D) presented total decreases in fluorescence loss after 28 days, indicating remineralization, the decrease in group C was the largest. The Kruskal-Wallis test yielded no significant differences between the three groups other than a significantly lower percentage of fluorescence loss in group C than in group D during the last assessment (T4). The untreated samples of control enamel (group A) revealed increasing percentages of fluorescence loss over the entire study period.
conclusionUse of the self-etching primers (groups B and C) was not associated with patterns of enamel demineralization different from those noted after traditional etching with phosphoric acid (group D). The only significant difference we observed was between the self-etching fluoride-releasing primer (group C) and traditional etching (group D) at the final assessment (T4). Thus, the fluoride-releasing system Transbond™ Plus was advantageous.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.