Evidence map›Paper›PMID 25158861›Full record

ArticleOral diseases2015

Detection of human papillomavirus in the oral cavities of persons with Fanconi anemia.

R L Winer, C E Huang, S Cherne, J E Stern, M S Butsch Kovacic, P A Mehta, S L Sauter, D A Galloway, R A Katzenellenbogen

Open access · greenAbstract read
In one paragraph

Article in Oral diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Oral human papillomavirus is common in individuals with Fanconi anemia.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

R L WinerDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
C E Huang
S Cherne
J E Stern
M S Butsch Kovacic
P A Mehta
S L Sauter
D A Galloway
R A Katzenellenbogen
University of Washington · USCincinnati Children's Hospital Medical Center · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAInfectious Disease Research Institute · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Fanconi Anemia as a Model for Susceptibility to Human Papillomavirus InfectionR01HL108102 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI BUTSCHKOVACIC, MELINDA SUE · 2011 to 2015
$1.9M
NCRR NIH HHS UL1 RR026314NCRR NIH HHS UL1 RR026314-01NHLBI NIH HHS R01 HL108102
6 · The paper itself

Abstract

objectiveWe conducted a cross-sectional study to describe the prevalence and correlates of type-specific human papillomavirus (HPV) DNA in the oral cavities of persons with Fanconi anemia. MATERIALS AND

methodsOral swabs were collected from 67 participants with Fanconi anemia and tested for 27 HPV genotypes using polymerase chain reaction-based methods.

resultsParticipants were a mean of 18.6 (standard deviation, 10.0) years of age (range 4-47 years). The prevalence of oral HPV infection was 7.5%, and the prevalence of high-risk HPV infection was 6.0%. HPV type 16 was not detected in any samples. Prevalence was higher in adults than in children (13.3% vs 2.7% in those ≥18 vs <18 years of age). Among adults, prevalence was higher in males than in females (25.0% vs 9.1%, respectively).

conclusionsPrevalence of oral HPV infection in persons with Fanconi anemia was comparable to estimates from other studies in the general population. However, in contrast to previous studies, we did not identify HPV type 16 (the type found in most HPV-related head and neck cancers) in any participants.

Indexed as

AdolescentAdultChildChild, PreschoolCross-Sectional StudiesFanconi AnemiaFemaleGenotypeHumansMaleMiddle AgedMouthMouth DiseasesPapillomaviridaePapillomavirus InfectionsPrevalenceFanconi anemiahead and neck squamous cell carcinomaoral human papillomavirus

Identifiers

PMID25158861
PMCPMC4344428
OpenAlexW2165692302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.