Evidence map›Paper›PMID 25158358›Full record

ReviewNature reviews. Neuroscience2014

Development of multisensory integration from the perspective of the individual neuron.

Barry E Stein, Terrence R Stanford, Benjamin A Rowland

Abstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed.

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  13. Integration of learned artificial sensation with vision during freely moving navigation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  14. Review
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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Barry E Stein
Terrence R Stanford
Benjamin A Rowland

Funding

SUPERIOR COLLICULUS--DEVELOPMENT OF VISUAL PROPERTIESR01NS036916 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEIN, BARRY E · 1999 to 2013
$4.9M
Processing Visual and Multisensory InformationR01EY016716 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEIN, BARRY E · 2007 to 2015
$3.8M
NEI NIH HHS EY016716NEI NIH HHS R01 EY016716NINDS NIH HHS NS036916NINDS NIH HHS R01 NS036916
6 · The paper itself

Abstract

The ability to use cues from multiple senses in concert is a fundamental aspect of brain function. It maximizes the brain’s use of the information available to it at any given moment and enhances the physiological salience of external events. Because each sense conveys a unique perspective of the external world, synthesizing information across senses affords computational benefits that cannot otherwise be achieved. Multisensory integration not only has substantial survival value but can also create unique experiences that emerge when signals from different sensory channels are bound together. However, neurons in a newborn’s brain are not capable of multisensory integration, and studies in the midbrain have shown that the development of this process is not predetermined. Rather, its emergence and maturation critically depend on cross-modal experiences that alter the underlying neural circuit in such a way that optimizes multisensory integrative capabilities for the environment in which the animal will function.

Indexed as

AnimalsBrainNeuronsPerceptionSensation

Identifiers

PMID25158358
PMCPMC4215474

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.