Evidence map›Paper›PMID 25157182›Full record

ArticleBlood2014

Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England.

Alyshah Abdul Sultan, Matthew J Grainge, Joe West, Kate M Fleming, Catherine Nelson-Piercy, Laila J Tata

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Management of obesity across women's life course: FIGO Best Practice Advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. The Risk of Thrombosis Around Pregnancy: Where Do We Stand?Frontiers in cardiovascular medicine · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Identification of Genetic Interaction with Risk Factors Using a Time-To-Event Model.International journal of environmental research and public health · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alyshah Abdul SultanDivision of Epidemiology and Public Health, University of Nottingham, City Hospital, Nottingham, United Kingdom; and.
Matthew J GraingeDivision of Epidemiology and Public Health, University of Nottingham, City Hospital, Nottingham, United Kingdom; and.
Joe WestDivision of Epidemiology and Public Health, University of Nottingham, City Hospital, Nottingham, United Kingdom; and.
Kate M FlemingDivision of Epidemiology and Public Health, University of Nottingham, City Hospital, Nottingham, United Kingdom; and.
Catherine Nelson-PiercyWomen's Health Academic Centre, Guy's & St. Thomas' Foundation Trust, St. Thomas' Hospital, London, United Kingdom.
Laila J TataDivision of Epidemiology and Public Health, University of Nottingham, City Hospital, Nottingham, United Kingdom; and.
University of Nottingham · GBNottingham City Hospital · GBGuy's and St Thomas' NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impact on the timing of first postpartum venous thromboembolism (VTE) for women with specific risk factors is of crucial importance when planning the duration of thromboprophylaxis regimen. We observed this using a large linked primary and secondary care database containing 222 334 pregnancies resulting in live and stillbirth births between 1997 and 2010. We assessed the impact of risk factors on the timing of postpartum VTE in term of absolute rates (ARs) and incidence rate ratios (IRRs) using a Poisson regression model. Women with preeclampsia/eclampsia and postpartum acute systemic infection had the highest risk of VTE during the first 3 weeks postpartum (ARs ≥2263/100 000 person-years; IRR ≥2.5) and at 4-6 weeks postpartum (AR ≥1360; IRR ≥3.5). Women with body mass index (BMI) >30 kg/m(2) or those having cesarean delivery also had elevated rates up to 6 weeks (AR ≥1425 at 1-3 weeks and ≥722 at 4-6 weeks). Women with postpartum hemorrhage or preterm birth, had significantly increased VTE rates only in the first 3 weeks (AR ≥1736; IRR ≥2). Our findings suggest that the duration of the increased VTE risk after childbirth varies based on the type of risk factors and can extend up to the first 3 to 6 weeks postpartum.

Indexed as

AdolescentAdultCohort StudiesEnglandFemaleHumansIncidenceMultivariate AnalysisNumbers Needed To TreatPostpartum PeriodPregnancyRisk FactorsTime FactorsVenous ThromboembolismYoung Adult

Identifiers

PMID25157182
PMCPMC4215315
OpenAlexW1982075510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.