ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2014
Endemic treponemal diseases.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- A systematic review and meta-analysis of sexually transmitted infections and blood-borne viruses in travellers.Journal of travel medicine · 2024Pooled it
- Metaanalysis of the Performance of a Combined Treponemal and Nontreponemal Rapid Diagnostic Test for Syphilis and Yaws.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Pooled it
- The Global Epidemiology of Syphilis in the Past Century - A Systematic Review Based on Antenatal Syphilis Prevalence.PLoS neglected tropical diseases · 2016Pooled it
- Scherlievo disease: A forgotten endemic treponematosis of the 18th-19th century Balkans.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Article
- Shotgun metagenomic analysis of the oral microbiomes of children with noma.PLoS neglected tropical diseases · 2026Article
- Dietary variability and micronutrient status of individuals with Yaws infection in Ghana: A case-control study.PloS one · 2025Article
- CDC Laboratory Recommendations for Syphilis Testing, United States, 2024.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2024Article
- Prospecting for yaws in the Mbaïki Health District in the Central African Republic.The Pan African medical journal · 2023Article
- Article
- The Depiction of Smallpox and Other Dermatologic Lesions on the Surfaces of Ancient Terracotta Statues from Mali, West Africa.Journal of community health · 2021Article
- Modeling Treatment Strategies to Inform Yaws Eradication.Emerging infectious diseases · 2020Article
- Geographically structured genomic diversity of non-human primate-infectingMicrobial genomics · 2020Article
- Multiplex Recombinase Polymerase Amplification Assay for Simultaneous Detection ofTropical medicine and infectious disease · 2020Article
- Multiplex Mediator Displacement Loop-Mediated Isothermal Amplification for Detection of Treponema pallidum and Haemophilus ducreyi.Emerging infectious diseases · 2020Article
- Article
- Health conditions and occupational risks in a novel group: waste pickers in the largest open garbage dump in Latin America.BMC public health · 2019Article
- Absence of Serological Evidence of Exposure toThe American journal of tropical medicine and hygiene · 2019Article
- Circulation of DistinctJournal of clinical microbiology · 2019Article
- Advances in the Treatment of Yaws.Tropical medicine and infectious disease · 2018Review
- Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania.Emerging infectious diseases · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
The endemic treponemal diseases, consisting of yaws, bejel (endemic syphilis) and pinta, are non-venereal infections closely related to syphilis, and are recognized by WHO as neglected tropical diseases (NTDs). Despite previous worldwide eradication efforts the prevalence of yaws has rebounded in recent years and the disease is now a major public health problem in 14 countries. Adequate data on the epidemiology of bejel and pinta is lacking. Each disease is restricted to a specific ecological niche but all predominantly affect poor, rural communities. As with venereal syphilis, the clinical manifestations of the endemic treponemal diseases are variable and can be broken down in to early stage and late stage disease. Current diagnostic techniques are unable to distinguish the different causative species but newer molecular techniques are now making this possible. Penicillin has long been considered the mainstay of treatment for the endemic treponemal diseases but the recent discovery that azithromycin is effective in the treatment of yaws has renewed interest in these most neglected of the NTDs, and raised hopes that global eradication may finally be possible.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.