Evidence map›Paper›PMID 25156987›Full record

Trial reportJournal of diabetes and its complications

Depression is not associated with diabetes control in minority elderly.

Priya Palta, Sherita Hill Golden, Jeanne A Teresi, Walter Palmas, Paula Trief, Ruth S Weinstock, Steven Shea, Jennifer J Manly, Jose A Luchsinger

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of diabetes and its complications. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Priya PaltaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sherita Hill GoldenDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD, USA; Department of Medicine, Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jeanne A TeresiResearch Division, Hebrew Home at Riverdale, Bronx, NY, USA; Morris W. Stroud, III, Center for Studies on Quality of Life, and New York State Psychiatric Institute, Columbia University, New York, NY, USA.
Walter PalmasDepartment of Medicine, Division of General Medicine, Columbia University School of Medicine, New York, NY, USA.
Paula TriefDepartment of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA; Department of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.
Ruth S WeinstockDepartment of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.
Steven SheaDepartment of Medicine, Division of General Medicine, Columbia University School of Medicine, New York, NY, USA; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Jennifer J ManlyDepartment of Neurology and Taub Institute, Division of Cognitive Neuroscience, Columbia University College of Physician and Surgeons, NY, USA; Gertrude H. Sergievksy Center, Columbia University Medical Center, New York, NY.
Jose A LuchsingerDepartment of Medicine, Division of General Medicine, Columbia University School of Medicine, New York, NY, USA; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA. Electronic address: jal94@columbia.edu.
Columbia University · USSUNY Upstate Medical University · USJohns Hopkins University · US

Funding

RESEARCH COREP60MD000206 · NIMHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LUCHSINGER, JOSE ALEJANDRO · 2003 to 2012
$16.2M
Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Clinical Research&Epidemiology in Diabetes&EndocrinologyT32DK062707 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Wendy Lynet Bennett · 2002 to 2026
$7.3M
NHLBI NIH HHS T32 HL007055NIDDK NIH HHS T32 DK062707NIMHD NIH HHS P60 MD 000206NIMHD NIH HHS P60 MD000206
6 · The paper itself

Abstract

aimsWe investigated the longitudinal association of depression, with and without cognitive dysfunction, with hemoglobin A1c (HbA1c), systolic blood pressure (SBP), and low-density lipoprotein (LDL) in a predominantly minority cohort.

methodsThere were 613 participants. Presence of depression was defined by a score ≥7 on the Short-CARE depression scale. We tested participants for executive dysfunction using the Color Trails Test (CTT), part 2, and for memory dysfunction using the total recall task of the Selective Reminding Test (TR-SRT). We classified performance in these tests as abnormal based on standardized score cutoffs (<16th percentile and one standard deviation below the sample mean). Random effects models were used to compare repeated measures of the diabetes control measures between those with depression versus those without depression and ever versus never cognitively impaired.

resultsBaseline depression was present in 36% of participants. Over a median follow-up of 2 years, depression was not related to worse HbA1c, SBP, or LDL. The presence of (1) abnormal performance on a test of executive function and depression (n=57) or (2) abnormal performance on a test of verbal recall and depression (n=43) was also not associated with clinically significant worse change in diabetes control.

conclusionsDepression, with or without low performance in tests of executive function and memory, may not affect clinically significant measures of diabetes control in the elderly.

Indexed as

Minority GroupsAgedAged, 80 and overBlood GlucoseComorbidityDepressionDepressive DisorderDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansLongitudinal StudiesMaleTelemedicineBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanCognitive dysfunctionDepressionDiabetesDiabetes controlOlder adults

Identifiers

PMID25156987
PMCPMC4310458
OpenAlexW2125229808

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.