ReviewAlcoholism, clinical and experimental research2014
Age-related effects of alcohol from adolescent, adult, and aged populations using human and animal models.
Review in Alcoholism, clinical and experimental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Age-related differences in the effect of chronic alcohol on cognition and the brain: a systematic review.Translational psychiatry · 2022Pooled it
- How adolescents' working memory abilities relate to their alcohol craving in real-life contexts depends on biological sex.Drug and alcohol dependence · 2021Trial
- Effects of cannabis smoke and oral Δ9THC on cognition in young adult and aged rats.Psychopharmacology · 2025Article
- Participant diversity in ACER: 2010-2022.Alcohol, clinical & experimental research · 2024Article
- Alcohol Triggers the Accumulation of Oxidatively Damaged Proteins in Neuronal Cells and Tissues.Antioxidants (Basel, Switzerland) · 2024Article
- Upregulation of mesencephalic astrocyte-derived neurotrophic factor (MANF) expression offers protection against alcohol neurotoxicity.Journal of neurochemistry · 2023Article
- The neuroimmune system - Where aging and excess alcohol intersect.Alcohol (Fayetteville, N.Y.) · 2023Review
- Prevalence and factors associated with substance use among HIV positive youth attending HIV care and treatment centers in Dodoma, Tanzania.AIDS research and therapy · 2022Article
- The importance of alcohol in elderly's hospital admissions for fall injuries: a population case-control study.Nordisk alkohol- & narkotikatidskrift : NAT · 2022Article
- Bayesian modelling of population trends in alcohol consumption provides empirically based country estimates for South Africa.Population health metrics · 2021Article
- Alcohol and Cannabis Use and the Developing Brain.Alcohol research : current reviews · 2021Review
- The laboratory rat: Age and body weight matter.EXCLI journal · 2021Review
- Sex and Age Effects on Neurobehavioral Toxicity Induced by Binge Alcohol.Brain plasticity (Amsterdam, Netherlands) · 2020Review
- Alcohol use among older adults: A comparative study across four European countries.Nordisk alkohol- & narkotikatidskrift : NAT · 2020Article
- Elevated alcohol consumption among geriatric psychiatric in-patients.Nordisk alkohol- & narkotikatidskrift : NAT · 2020Article
- Alcohol use in young adults associated with cortical gyrification.Drug and alcohol dependence · 2020Article
- Acute alcohol exposure dose-dependently alleviates social avoidance in adolescent mice and inhibits social investigation in adult mice.Psychopharmacology · 2019Article
- Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.International review of neurobiology · 2019Review
- A comparison of hippocampal microglial responses in aged and young rodents following dependent and non-dependent binge drinking.International review of neurobiology · 2019Article
- Late aging alters behavioral sensitivity to ethanol in a sex-specific manner in Fischer 344 rats.Pharmacology, biochemistry, and behavior · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThis review incorporates current research examining alcohol's differential effects on adolescents, adults, and aged populations in both animal and clinical models.
methodsThe studies presented range from cognitive, behavioral, molecular, and neuroimaging techniques, leading to a more comprehensive understanding of how acute and chronic alcohol use affects the brain throughout the life span.
resultsAge of life is a significant factor in determining the effect of alcohol on brain functioning. Adolescents and aged populations may be more negatively affected by heavy alcohol use when compared to adults.
conclusionsInvestigations limiting alcohol effects to a single age group constrains understanding of differential trajectories and outcomes following acute and chronic use. To meaningfully address the sequencing and interaction effects of alcohol and age, the field must incorporate collaborative and integrated research efforts focused on interdisciplinary questions facilitated by engaging basic and applied scientists with expertise in a range of disciplines including alcohol, neurodevelopment, and aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.