ArticleTissue engineering. Part C, Methods2015
Fabrication of cell-laden macroporous biodegradable hydrogels with tunable porosities and pore sizes.
Article in Tissue engineering. Part C, Methods, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Facile and Green Fabrication of Porous Hydrogels Based on Gelatin Microsphere Porogens for 3D Immune Cell Culture.Gels (Basel, Switzerland) · 2026Article
- Synergistic effect of Hypoxic Conditioning and Cell-Tethering Colloidal Gels enhanced Productivity of MSC Paracrine Factors and Accelerated Vessel Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Hydrogel: A Potential Material for Bone Tissue Engineering Repairing the Segmental Mandibular Defect.Polymers · 2022Review
- PLGA/TiOBioImpacts : BI · 2021Article
- Hydrogel microparticles for biomedical applications.Nature reviews. Materials · 2020Article
- It's All in the Delivery: Designing Hydrogels for Cell and Non-viral Gene Therapies.Molecular therapy : the journal of the American Society of Gene Therapy · 2018Review
- Recent Progress in Developing Injectable Matrices for Enhancing Cell Delivery and Tissue Regeneration.Advanced healthcare materials · 2018Review
- Evaluation of Gelatin Microparticles as Adherent-Substrates for Mesenchymal Stem Cells in a Hydrogel Composite.Annals of biomedical engineering · 2016Article
- Cellularizing hydrogel-based scaffolds to repair bone tissue: How to create a physiologically relevant micro-environment?Journal of tissue engineeringArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
In this work, we investigated a cytocompatible particulate leaching method for the fabrication of cell-laden macroporous hydrogels. We used dehydrated and uncrosslinked gelatin microspheres as leachable porogens to create macroporous oligo(poly(ethylene glycol) fumarate) hydrogels. Varying gelatin content and size resulted in a wide range of porosities and pore sizes, respectively. Encapsulated mesenchymal stem cells (MSCs) exhibited high viability immediately following the fabrication process, and culture of cell-laden hydrogels revealed improved cell viability with increasing porosity. Additionally, the osteogenic potential of the encapsulated MSCs was evaluated over 16 days. Overall, this study presents a robust method for the preparation of cell-laden macroporous hydrogels with desired porosity and pore size for tissue engineering applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.