ReviewJournal of neuroimmunology2014
Ventricular shunt infections: immunopathogenesis and clinical management.
Review in Journal of neuroimmunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- An Antibiotic Prophylaxis for Prevention of Ventriculoperitoneal Shunt Infection Using Intraventricular Injection and Shunt Soaking with Vancomycin and Gentamicin.Antibiotics (Basel, Switzerland) · 2026Article
- Article
- Expression of Human Myxovirus Resistance Protein 1 (MxA) in Shunt Infections.Annals of Indian Academy of Neurology · 2025Article
- Management of Recurrent Ventriculoperitoneal Shunt Infections in Adult Patients.Antibiotics (Basel, Switzerland) · 2025Article
- Atypical delayed ventriculoperitoneal shunt infection following hysteroscopic polypectomy: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Review
- Complications of ventriculoperitoneal shunts: Infection and exposure in hydrocephalus patients: A case series.Surgical neurology international · 2024Article
- Article
- Article
- Efficacy of antimicrobial medicated ventricular catheters: a network meta-analysis with trial sequential analysis.Neurosurgical review · 2022Review
- Application of magnetically actuated self-clearing catheter for rapid in situ blood clot clearance in hemorrhagic stroke treatment.Nature communications · 2022Article
- Bacterial translocation as a cause of ventriculoperitoneal shunt infection: A case report.Clinical case reports · 2022Article
- The Prospect of Nanoparticle Systems for Modulating Immune Cell Polarization During Central Nervous System Infection.Frontiers in immunology · 2021Article
- Global trends in the evaluation and management of cerebrospinal fluid shunt infection: a cooperative ISPN survey.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- A Plastic-neuro Effort: Vascularized Soft-tissue Coverage for Hostile Wound Bed with Multiple Ventricular Shunt Failures.Plastic and reconstructive surgery. Global open · 2020Article
- Self-defensive antimicrobial biomaterial surfaces.Colloids and surfaces. B, Biointerfaces · 2020Article
- From the heart to the bladder-particularities of ventricular shunt topography and the current status of cerebrospinal fluid diversion sites.Neurosurgical review · 2020Review
- Rates of cerebrospinal fluid infection and the causative organisms following shunt procedures in Saudi Arabia. A retrospective study based on radiological findings.Saudi medical journal · 2020Article
- Towards zero infection for ventriculoperitoneal shunt insertion in resource-limited settings: a multicenter prospective cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Toll-like receptor linked cytokine profiles in cerebrospinal fluid discriminate neurological infection from sterile inflammation.Brain communications · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Ventricular shunts are the most common neurosurgical procedure performed in the United States. This hydrocephalus treatment is often complicated by infection of the device with biofilm-forming bacteria. In this review, we discuss the pathogenesis of shunt infection, as well as the implications of the biofilm formation on treatment and prevention of these infections. Many questions remain, including the contribution of glia and the impact of inflammation on developmental outcomes following infection. Immune responses within the CNS must be carefully regulated to contain infection while minimizing bystander damage; further study is needed to design optimal treatment strategies for these patients.
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Registered trials
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