Trial reportResearch in nursing & health2014
Dietary fiber supplementation for fecal incontinence: a randomized clinical trial.
Trial report in Research in nursing & health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03543566 (Antimuscarinic Medication for Urgency Urinary Incontinence in Women With Dual Incontinence), which is not on this map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Antimuscarinic Medication for Urgency Urinary Incontinence in Women With Dual Incontinence (Darifenacin for Treatment of Women With Dual Incontinence)
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- The Efficacy of Gum Arabic in Managing Diseases: A Systematic Review of Evidence-Based Clinical Trials.Biomolecules · 2023Pooled it
- Guideline for the diagnosis and treatment of Faecal Incontinence-A UEG/ESCP/ESNM/ESPCG collaboration.United European gastroenterology journal · 2022Guideline
- Role of diet in fecal incontinence: a systematic review of the literature.International urogynecology journal · 2016Pooled it
- In vitro degradation and fermentation of three dietary fiber sources by human colonic bacteria.Journal of agricultural and food chemistry · 2013Trial
- Dietary Inflammatory Potential and Continence-Related Symptoms: Cross-Sectional and Longitudinal Analyses of Three Population Studies.Food science & nutrition · 2026Article
- Low Anterior Resection Syndrome Evaluation and Management.Clinics in colon and rectal surgery · 2026Review
- The Japan Society of Coloproctology Practice Guidelines for Fecal Incontinence 2024 (Revised Second Edition).Journal of the anus, rectum and colon · 2026Review
- Pharmacotherapy for fecal incontinence: potential treatment with a traditional Japanese medicine Kampo.Annals of coloproctology · 2025Review
- Structural and Functional Properties of Fiber From Psyllium (Plantago ovata) Husk: Current Knowledge and Strategies to Expand Its Application in Food and Beyond.Comprehensive reviews in food science and food safety · 2025Review
- Review
- Article
- Pelvic Floor Therapy and Initial Interventions for Pelvic Floor Dysfunction in Gynecologic Malignancies.Current oncology reports · 2024Review
- Garg incontinence scores: New scoring system on the horizon to evaluate fecal incontinence. Will it make a difference?World journal of gastroenterology · 2024Review
- Nutrition and Disorders of Gut-Brain Interaction.Nutrients · 2024Review
- The Impact of Nutritional Therapy on Gastrointestinal Motility in Older Adults.Healthcare (Basel, Switzerland) · 2023Review
- Clinical Management of Low Anterior Resection Syndrome: Review of the Current Diagnosis and Treatment.Cancers · 2023Review
- Management of Low Anterior Resection Syndrome (LARS) Following Resection for Rectal Cancer.Cancers · 2023Review
- Faecal incontinence in adults.Nature reviews. Disease primers · 2022Review
- The Association Between Dietary Intake and Improvement of LARS Among Rectal Cancer Patients After Sphincter-Saving Surgery-A Descriptive Cohort Study.Frontiers in surgery · 2022Article
- Dietary fibre in gastrointestinal health and disease.Nature reviews. Gastroenterology & hepatology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Dietary fiber supplements are used to manage fecal incontinence (FI), but little is known about the fiber type to recommend or the level of effectiveness of such supplements, which appears related to the fermentability of the fiber. The aim of this single-blind, randomized controlled trial was to compare the effects of three dietary fiber supplements (carboxymethylcellulose [CMC], gum arabic [GA], or psyllium) with differing levels of fermentability to a placebo in community-living individuals incontinent of loose/liquid feces. The primary outcome was FI frequency; secondary outcomes included FI amount and consistency, supplement intolerance, and quality of life (QoL). Possible mechanisms underlying supplement effects were also examined. After a 14-day baseline, 189 subjects consumed a placebo or 16 g total fiber/day of one of the fiber supplements for 32 days. FI frequency significantly decreased after psyllium supplementation versus placebo, in both intent-to-treat and per-protocol mixed model analyses. CMC increased FI frequency. In intent-to-treat analysis, the number of FI episodes/week after supplementation was estimated to be 5.5 for Placebo, 2.5 for Psyllium, 4.3 for GA, and 6.2 for CMC. Only psyllium consumption resulted in a gel in feces. Supplement intolerance was low. QoL scores did not differ among groups. Patients with FI may experience a reduction in FI frequency after psyllium supplementation, and decreased FI frequency has been shown to be an important personal goal of treatment for patients with FI. Formation of a gel in feces appears to be a mechanism by which residual psyllium improved FI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.