Trial reportSurgical endoscopy2015
Comparison between intraoperative cholangiography and choledochoscopy for ductal clearance in laparoscopic CBD exploration: a prospective randomized study.
Trial report in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Comparative clinical outcomes of transcystic vs. transductal laparoscopic common bile duct exploration: a retrospective study.BMC gastroenterology · 2025Article
- National trends in utilization and readmission following intraoperative cholangiography in gallstone pancreatitis.Surgery open science · 2025Article
- Surgical strategies for challenging common bile duct stones in the endoscopic era: A comprehensive review of current evidence.World journal of gastrointestinal endoscopy · 2024Review
- Residual choledocholithiasis after choledocholithotomy T-tube drainage: what is the best intervention strategy?BMC gastroenterology · 2022Article
- Surgical methods of treatment for cholecystolithiasis combined with choledocholithiasis: six years' experience of a single institution.Surgical endoscopy · 2022Article
- Epidemiological Survey of Different Treatments for Choledocholithiasis in Taiwan: A Nationwide, Population-Based Cohort Analysis.Journal of clinical medicine · 2022Article
- Dual common bile duct examination with transcystic choledochoscopy and cholangiography in laparoscopic cholecystectomy for suspected choledocholithiasis: a prospective study.Surgical endoscopy · 2021Article
- An analysis of the incidence, causes and preventative approaches to gram-negative bloodstream infections of hepatopancreatobiliary origin.Journal of infection prevention · 2021Article
- Surgical (Open and laparoscopic) management of large difficult CBD stones after different sessions of endoscopic failure: A retrospective cohort study.Annals of medicine and surgery (2012) · 2019Article
- Laparoscopic surgery for choledocholithiasis concomitant with calculus of the left intrahepatic duct or abdominal adhesions.Surgical endoscopy · 2017Article
- Primary Closure Following Laparoscopic Common Bile Duct Exploration Combined with Intraoperative Choledochoscopy and D-J Tube Drainage for Treating Choledocholithiasis.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Laparoscopic common bile duct exploration: a safe and definitive treatment for elderly patients.Surgical endoscopy · 2017Article
- Role of laparoscopic common bile duct exploration in the management of choledocholithiasis.World journal of gastrointestinal surgery · 2016Review
- Eleven years of primary closure of common bile duct after choledochotomy for choledocholithiasis.Surgical endoscopy · 2016Article
- Outcomes of Laparoscopic Common Bile Duct Exploration by Chopstick Technique in Choledocholithiasis.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic CBD exploration (LCBDE) is an accepted treatment modality for single stage management of CBD stones in fit patients. A transcholedochal approach is preferred in patients with a dilated CBD and large impacted stones in whom ductal clearance remains problematic. There are very few studies comparing intraoperative cholangiography (IOC) with choledochoscopy to determine ductal clearance in patients undergoing transcholedochal LCBDE. This series represents the first of those comparing the two from Asia.
methodsBetween April 2009 and October 2012, 150 consecutive patients with CBD stones were enrolled in a prospective randomized study to undergo transcholedochal LCBDE on an intent-to-treat basis. Patients with CBD diameter of less than 9 mm on preoperative imaging were excluded from the study. Out of the 132 eligible patients, 65 patients underwent IOC (Group A), and 67 patients underwent intraoperative choledochoscopy (Group B) to determine CBD clearance.
resultsThere were no differences between the two groups in the demographic profile and the preoperative biochemical findings. There was no conversion to open procedures, and complete stone clearance was achieved in all the 132 cases. The mean CBD diameter and the mean number of CBD stones removed were comparable between the two groups. Mean operating time was 170 min in Group A and 140 min in Group B (p < 0.001). There was no difference in complications between the two groups. Nine patients in Group A (13.8%) showed non-passage of contrast into the duodenum on IOC which resolved after administration of i.v. glucagon, suggesting a transient spasm of sphincter of Oddi. Two patients (3%) showed a false-positive result on IOC which had to be resolved with choledochoscopy.
conclusionsThe present study showed that intraoperative choledochoscopy is better than IOC for determining ductal clearance after transcholedochal LCBDE and is less cumbersome and less time-consuming.
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